Dr. Ralph A DeFronzo, MD
Claim this profileThe University of Texas Health Science Center at San Antonio
Studies Type 2 Diabetes
Studies Diabetes
10 reported clinical trials
14 drugs studied
Affiliated Hospitals
Clinical Trials Ralph A DeFronzo, MD is currently running
SGLT2 Inhibitors
for Heart Failure
This trial uses empagliflozin to help people with Type 2 Diabetes and Heart Failure. The medication increases blood ketone levels, which may improve muscle and heart function, exercise capacity, and overall well-being. Empagliflozin has been shown to reduce cardiovascular death and hospitalization for heart failure in patients with type 2 diabetes.
Recruiting0 awards Phase < 19 criteria
Empagliflozin
for Type 2 Diabetes
In this study, we will test the hypothesis that distinct mechanisms account for the SGLT2i-induced stimulation of ketogenesis and lipolysis versus endogenous (hepatic) glucose production in patients with type 2 diabetes (T2D) and type 1 diabetes (T1D), and that the increases in ketone production and lipolysis can be prevented by concomitant administration of the thiazolidinedione pioglitazone. We will conduct five distinct experiments to test this hypothesis in patients with T2D and T1D. MAIN STUDY: To examine the effect of empagliflozin versus empagliflozin/pancreatic clamp on EGP (6,6, D2-glucose), gluconeogenesis (D2O), lipolysis (U-2H-glycerol), ketogenesis (13C-palmitate conversion to 3-betahydroxybuyrate), and norepinephrine turnover (3H-NE) in type 2 diabetes subjects.
Recruiting0 awards Phase 19 criteria
More about Ralph A DeFronzo, MD
Clinical Trial Related1 year of experience running clinical trials · Led 10 trials as a Principal Investigator · 3 Active Clinical TrialsTreatments Ralph A DeFronzo, MD has experience with
- Dapagliflozin
- Placebo
- Empagliflozin
- Metformin
- Pioglitazone
- Saxagliptin
Breakdown of trials Ralph A DeFronzo, MD has run
Type 2 Diabetes
Diabetes
Insulin Resistance
Impaired Glucose Tolerance
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Ralph A DeFronzo, MD specialize in?
Ralph A DeFronzo, MD focuses on Type 2 Diabetes and Diabetes. In particular, much of their work with Type 2 Diabetes has involved treating patients, or patients who are undergoing treatment.
Is Ralph A DeFronzo, MD currently recruiting for clinical trials?
Yes, Ralph A DeFronzo, MD is currently recruiting for 3 clinical trials in San Antonio Texas. If you're interested in participating, you should apply.
Are there any treatments that Ralph A DeFronzo, MD has studied deeply?
Yes, Ralph A DeFronzo, MD has studied treatments such as Dapagliflozin, Placebo, Empagliflozin.
What is the best way to schedule an appointment with Ralph A DeFronzo, MD?
Apply for one of the trials that Ralph A DeFronzo, MD is conducting.
What is the office address of Ralph A DeFronzo, MD?
The office of Ralph A DeFronzo, MD is located at: The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 United States. This is the address for their practice at the The University of Texas Health Science Center at San Antonio.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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