Tinnitus

Los Angeles, CA

2 Tinnitus Trials near Los Angeles, CA

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No Placebo
Highly Paid
Stay on Current Meds
Pivotal Trials (Near Approval)
Breakthrough Medication
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life. Despite too many research projects on finding the mechanism of tinnitus, its pathophysiology remains poorly understood. It is well understood that many factors, such as poor education, lower income, or occupational, and recreational activity associated with high noise exposure, influence the prevalence and risk of tinnitus. Although the economic and emotional impact of tinnitus is large, there is currently no FDA-approved medication to treat this condition. However, there are pharmacological options to address the stress, anxiety, and depression that are caused by tinnitus. In this project, the investigators intend to use medications for patients with acute tinnitus to decrease the impact of tinnitus in their daily lives and activities. There are some studies on medications treating tinnitus; however, there are few randomized clinical trials to prove the efficacy of the treatment. The frequency and loudness of tinnitus will be measured before and after the course. Functional MRI of the brain will be obtained to view any changes that may occur before and after the treatment.
No Placebo Group

Trial Details

Trial Status:Recruiting
Trial Phase:Phase 4
Age:25 - 85

100 Participants Needed

This trial is testing if playing sounds through headphones or using small electrical currents in the ear can help people with tinnitus. It targets those whose tinnitus significantly affects their quality of life. The treatment works by trying to interfere with the ringing noise, making it quieter or stopping it. Using small electrical currents has been explored in various studies as a potential treatment for tinnitus, showing mixed results in terms of effectiveness.
No Placebo Group

Trial Details

Trial Status:Active Not Recruiting
Trial Phase:Unphased

100 Participants Needed

Why Other Patients Applied

"As a healthy volunteer, I like to participate in as many trials as I'm able to. It's a good way to help research and earn money."

IZ
Healthy Volunteer PatientAge: 38

"I was diagnosed with stage 4 pancreatic cancer three months ago, metastatic to my liver, and I have been receiving and responding well to chemotherapy. My blood work revealed that my tumor markers have gone from 2600 in the beginning to 173 as of now, even with the delay in treatment, they are not going up. CT Scans reveal they have been shrinking as well. However, chemo is seriously deteriorating my body. I have 4 more treatments to go in this 12 treatment cycle. I am just interested in learning about my other options, if any are available to me."

ID
Pancreatic Cancer PatientAge: 40

"I changed my diet in 2020 and I’ve lost 95 pounds from my highest weight (283). I am 5’3”, female, and now 188. I still have a 33 BMI. I've been doing research on alternative approaches to continue my progress, which brought me here to consider clinical trials."

WR
Obesity PatientAge: 58

"I've tried several different SSRIs over the past 23 years with no luck. Some of these new treatments seem interesting... haven't tried anything like them before. I really hope that one could work."

ZS
Depression PatientAge: 51

"My orthopedist recommended a half replacement of my right knee. I have had both hips replaced. Currently have arthritis in knee, shoulder, and thumb. I want to avoid surgery, and I'm open-minded about trying a trial before using surgery as a last resort."

HZ
Arthritis PatientAge: 78

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Frequently Asked Questions

How much do Tinnitus clinical trials in Los Angeles, CA pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range for Phase 2–4 trials (Phase 1 trials often pay substantially more). Further, most trials will cover the costs of a travel to-and-from the clinic.

How do Tinnitus clinical trials in Los Angeles, CA work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll be sorted into one of the treatment groups, and receive your study drug. For some trials, there is a chance you'll receive a placebo. Across Tinnitus trials in Los Angeles, CA 30% of clinical trials have a placebo. Typically, you'll be required to check-in with the clinic every month or so. The average trial length in Los Angeles, CA for Tinnitus is 12 months.

How do I participate in a study as a "healthy volunteer"?

Not all studies recruit healthy volunteers: usually, Phase 1 studies do. Participating as a healthy volunteer means you will go to a research facility in Los Angeles, CA several times over a few days or weeks to receive a dose of either the test treatment or a "placebo," which is a harmless substance that helps researchers compare results. You will have routine tests during these visits, and you'll be compensated for your time and travel, with the number of appointments and details varying by study.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in to get approval for a specific condition. Phase 1 trials are the trials to collect safety data in humans. Phase 2 trials are those where the drug has some data showing safety in humans, but where further human data is needed on drug effectiveness. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. As a general rule, Phase 3 trials are more promising than Phase 2, and Phase 2 trials are more promising than phase 1.

Do I need to be insured to participate in a Tinnitus medical study in Los Angeles, CA?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

What are the newest Tinnitus clinical trials in Los Angeles, CA?

Most recently, we added Migraine Medications for Tinnitus and Acoustic + Electrical Stimulation for Tinnitus to the Power online platform.

Are there trials for tinnitus?

Yes—well over 100 clinical studies for tinnitus (from quick online surveys to device or medication trials) are recruiting worldwide. The fastest way to see what’s open is to type “tinnitus” into ClinicalTrials.gov or the WHO international registry and filter for “recruiting,” then contact the listed study team or ask your ENT/audiologist if you meet their inclusion rules. Before signing up, weigh the possible benefits against travel, time, and the chance of receiving a placebo, and be sure to read the informed-consent form carefully.

What is the simple trick to stop tinnitus?

There is no single “simple trick” that reliably switches tinnitus off, but you can make it less intrusive by calming your body and giving your ears something else to focus on: try slow belly-breathing, add gentle background sound (fan, soft music, white-noise app), and relax tight neck-jaw muscles. If the ringing is new, one-sided, pulsates with your heartbeat, or comes with sudden hearing loss, see a doctor promptly; otherwise, longer-term relief often comes from structured programs such as cognitive-behavioural therapy, sound therapy, or hearing aids that address both the noise and the stress it causes.

At what point is tinnitus permanent?

Doctors label tinnitus “chronic” once it has persisted for about six months; after that point it rarely goes away on its own, although many people can still reduce how much it bothers them with treatment. Ringing that begins after loud noise or an ear infection usually settles within minutes, days, or at most a few weeks—so if yours lasts longer than two weeks, or is paired with new hearing loss, see an audiologist or ENT promptly to look for reversible causes and start proven coping strategies before it becomes long-term.

Has anyone reversed tinnitus?

Yes—tinnitus can and does disappear for some people, especially when the underlying cause (e.g., ear-wax, middle-ear infection, medication side-effect, sudden hearing loss or jaw/neck problems) is found and fixed, and about 1 in 5 new cases fade on their own within a year. Even when it persists, most patients can make it much less intrusive by combining ear-focused measures (hearing aids, sound or masking devices) with brain-focused approaches like cognitive-behavioural therapy or tinnitus-retraining therapy, so the key first step is a thorough exam by an ENT/audiologist to look for reversible triggers and then choose the right management tools.

What is the drug of choice for tinnitus?

There is actually no single “drug of choice” for tinnitus—no medicine has been proven to reliably silence the ringing, and any drug use is off-label and aimed at easing related problems such as anxiety, depression, or poor sleep. Doctors first recommend non-drug strategies (hearing aids, background sound generators, cognitive-behavioral therapy) and then may trial medicines like a tricyclic antidepressant (e.g., nortriptyline), a benzodiazepine (e.g., clonazepam), or gabapentin in selected patients who are very distressed, monitoring closely for side-effects. Work with an ENT or audiologist to create a plan that addresses both the noise and its emotional impact rather than relying on a single pill.

Is tinnitus a legal disability?

Tinnitus can qualify as a legal disability when the ringing is severe enough to limit your ability to work or perform major life activities, but the exact test depends on the system making the decision. For Social Security (SSDI/SSI) you must show medical proof of the condition and that it stops you from “substantial gainful activity” for at least 12 months; under the ADA the same medical evidence can trigger workplace accommodations; and the VA automatically grants a 10 % rating if the tinnitus is service-connected, with higher benefits possible if it prevents employment. In every case, detailed ENT or audiology records, treatment history, and statements describing how the noise affects concentration, sleep, balance, or communication are what turn tinnitus from a symptom into a legally recognized disability.

Do tinnitus ear drops work?

Off-the-shelf “tinnitus ear drops” have never been shown in good studies to quiet chronic ringing, and standard prescription drops help only when they treat a reversible ear problem—think wax blockage or an outer-ear infection that is causing or amplifying the noise. If the tinnitus comes from inner-ear damage or brain pathways (the usual case), drops won’t work; proven relief instead comes from strategies like hearing aids, sound therapy, or tinnitus-focused CBT after an ENT or audiology evaluation. Seek prompt medical review if the ringing is one-sided, pulsating, or tied to sudden hearing loss, and avoid unregulated drops that can irritate the canal.

Is tinnitus hard to prove?

Most tinnitus is “subjective,” meaning only you can hear it, so a doctor can’t capture the sound itself—but they can still document it by showing related hearing changes on an audiogram, matching the pitch/loudness of the ringing, and scoring its impact with validated questionnaires such as the Tinnitus Handicap Inventory. This bundle of test results is usually enough for a formal diagnosis and for insurance or disability claims; only in the uncommon “objective” form can a clinician actually hear the noise through a stethoscope or microphone.

What is the new cure for tinnitus?

There is still no permanent cure for tinnitus, but the newest FDA-cleared treatment is Lenire, a headset that pairs tailored sounds with gentle electrical pulses to the tongue; in a 326-person randomized study, about 70 % of users had a meaningful drop in symptom scores after 12 weeks, and benefits often persisted for a year with minimal side effects. Results vary—ringing rarely disappears completely—so specialists still rely on hearing aids, sound-therapy apps, and cognitive-behavioral techniques when Lenire isn’t available or sufficient. Discuss the pros, cost, and suitability of each option with an ENT or audiologist to decide what’s realistic for you.

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