Testosterone Clinical Trials

Testosterone studies recruiting patients for novel treatments. Filter by phase, distance, and inclusion criteria to find your perfect testosterone clinical trial.

Reviewed by Michael Gill, B. Sc.
10 Testosterone Clinical Trials Near Me

What Are Testosterone Clinical Trials?

Testosterone is one of the fundamental male sex hormones responsible for muscle mass, fertility, red blood cell production, and fat distribution. If the testosterone levels drop too low, it can lead to many different medical conditions and problems like infertility and hypogonadism.

Since the problem of low testosterone is becoming widespread, it is important to conduct testosterone clinical trials since it has a huge impact on male fertility. Testosterone levels worldwide are dropping among males, which is why testosterone clinical trials are vital in learning more about what causes it, how to cure it, and how to improve the quality of life for many.

Why Is Testosterone Being Studied in Clinical Trials?

Deficiency of testosterone ranges from 10-40% globally. One study has revealed that testosterone levels in men have been on a substantial decline for decades, averaging around 1% a year.

Low testosterone can result in symptoms such as below:

  • Fatigue
  • Irritability
  • Reduced sex drive
  • Low lean muscle mass
  • Depression
  • Erectile dysfunction

It can be caused by many different factors like congenital conditions, diabetes, obesity, and damage or loss to the testicles.

How Does Testosterone Treatment Work?

People experiencing low testosterone can get Testosterone Replacement Therapy. It comes in the form of gels, patches, pellets, and injections. It is known to improve the symptoms of LT, evening increasing muscle strength and size as well as decreasing fat mass.

What Are Some of the Breakthrough Clinical Trials Involving Testosterone?

2023: Adverse cardiovascular events and mortality in men during testosterone treatment: an individual patient and aggregate data meta-analysis – The study found that men can get short-to-medium testosterone hormone therapy with no greater risk for cardiovascular diseases such as stroke and heart attacks.

2020: A new oral testosterone undecanoate therapy comes of age for the treatment of hypogonadal men – New testosterone undecanoate oral formula was effective and safe for hypogonadal treatment. The research studied the short and long-term effects of the drug on hypogonadal men. There were no findings of liver toxicity.

2019: The Testosterone Trials of Older Men – This ongoing trial is testing whether testosterone therapy can benefit older men with unequivocally low levels of the hormone. The sample is men who have experienced measured abnormalities in any one of five key areas: vitality, sexual or physical function, anemia, and cognition.

Who Are the Key Opinion Leaders On Testosterone Clinical Trial Research?

American Urology Association offers a database of knowledge on testosterone and is continuously working on improving symptoms of low testosterone.

Endocrine Center has ongoing studies on low testosterone and how to effectively treat it among men. They also provide information about low testosterone, creating awareness and gathering funds for further research.

The National Cancer Institute is working on research underlining the benefits of testosterone therapy for prostate cancer.

About The Author

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 25th, 2021

Last Reviewed: August 13th, 2023