Prevention Clinical Trials
Here are the 6 most popular medical studies for prevention
Vitamin
Vitamin D + Fish Oil for Health Improvement
This trial is studying whether taking daily dietary supplements of vitamin D3 or omega-3 fatty acids reduces the risk of developing cancer, heart disease, and stroke in people who do not have a prior history of these illnesses.
Behavioral Intervention
Improved Perioperative Preventive Measures for Surgical Site Infections
This trial is testing a multifaceted program to see if it can reduce surgical site infections (SSIs). The program includes improved basic perioperative preventive measures. The investigators aim to examine the relative effectiveness of each component of this program in controlling ESKAPE transmission and reducing SSIs and to identify an optimal implementation strategy for national dissemination.
Behavioural Intervention
Fall Prevention Program for Older Adults
This trial is studying a new way to prevent falls in older adults that includes an evaluation by a physical therapist and pharmacist in addition to the usual care by an ED clinician. The study will last for 12 months and measure recurrent falls.
Behavioral Intervention
Fuerte Program for Psychological Trauma in Immigrant Youth
This trial will test the efficacy of a school-based group prevention program called Fuerte, which is designed to help newcomer Latinx immigrant youth who are at risk of experiencing traumatic stress. The program will be implemented by mental health providers from various county community-based organizations, as well as from the SFUSD Wellness Centers.
Behavioral Intervention
Behavioral Activation for Alcohol Use Disorder
This trial will test a new way to help college freshmen who drink too much alcohol. The intervention will address concerns that are most relevant to these students and be integrated into the college curriculum.
Popular filter options for prevention trials
Prediabetes Clinical Trials
View 7 Prediabetes medical studies.
Biguanides
Lifestyle Changes + Metformin for Diabetes Prevention
This trial looks at the ability of an intensive lifestyle or metformin to prevent or delay the development of diabetes in a high risk population. Lifestyle reduced diabetes onset by 58% and metformin reduced diabetes onset by 31%.
Behavioral Intervention
Diabetes Genetic Counseling for Obesity
This study will examine the impact diabetes genetic counseling on patient motivation and disease prevention behaviors among subjects with pre-diabetes. Intervention subjects will be provided with their individual diabetes genotype risk score derived from aggregating the combined results of 37 diabetes risk-associated genetic loci. Controls will not be tested. All subjects will be enrolled in a 12-week diabetes prevention program.
Behavioral Intervention
Peer-led intervention +1 More for Diabetes
The prevalence of obesity and diabetes in older adults is increasing. Because older adults are often portrayed as less likely to change long-standing health behaviors, health promotion in this age group has lagged behind others. In fact, little attention has been given to the importance of diabetes prevention in community-dwelling older adults through the implementation of programs that promote healthy nutrition, increase physical activity and improve self-management. The Diabetes Prevention Program (DPP), which demonstrated the benefit of modest weight loss on the reduction of diabetes risk (58% overall reduction with a 71% reduction in the older population), has yet to be translated into widespread public health practice. The overall objective of this protocol is to implement evidence-informed, innovative interventions to increase adoption of findings from comparative effectiveness research (CER) for diabetes management and prevention in South Florida older veterans. Specifically, the proposed study will test the hypothesis that Peer-led Care alone (PC), or activated by technology (TechnAlert-Peer or TAP), is superior to traditional methods of information dissemination (Usual Care or UC) for adoption of CER on prevention and management of diabetes, leading to better self-efficacy and clinical outcomes. The investigators will conduct a 12-month randomized controlled trial in older veterans with prediabetes and diabetes participating in one of the Healthy Aging Regional Collaborative programs. Primary outcomes include changes in self-efficacy, weight, and hemoglobin A1c. Secondary outcomes include changes in blood pressure, lipids, physical function, quality of life, and health care utilization and the evaluation of potential racial/ethnic disparities in the process of adoption of CER for prevention and management of diabetes. This study is expected to accelerate the implementation of CER evidence for diabetes prevention, addressing health and economic challenges in the care of overweight and obese veterans.
Obesity Clinical Trials
View 6 Obesity medical studies.
Behavioral Intervention
Dissonance-Based Obesity Prevention + Response and Attention Training for Obesity
This trial is testing whether a novel obesity prevention program is more effective when done in single-sex versus mixed-sex groups, and whether adding food response and attention training increases weight gain prevention effects.
Behavioural Intervention
PEER group intervention for Obesity
Project PEER utilizes a randomized controlled study design to investigate the combined effects of an exercise and nutrition intervention that is based on self-efficacy principles and delivered primarily by peer educators to reduce the risk for obesity in female college freshman over one academic year (N = 300). The control group will receive minimal interaction from the research team, paralleling the typical freshman experience on the UIUC campus. Recruitment will take place in two waves (consecutive fall terms with n = 150). During the final year (Fall 2010) of the project, a General Education course will be offered that targets weight management. Importantly, the discussion groups for this course will be taught by peer educators trained using the peer resources further refined during the PEER project. In addition to conventional measures of content knowledge assessed in the college classroom when obtaining class credit, personal physical activity and nutrition behaviors along with behavioral determinants (self-efficacy, self-regulatory skills and outcome expectations) will also be assessed. Primary Aim 1: To determine the effectiveness of a peer-delivered self efficacy-based behavioral intervention to enhance nutrition and physical activity behaviors and subsequently weight management success in female university freshman over one academic year. We hypothesize that freshmen randomized to the intervention group will be more successful in losing or maintaining weight than the control group through a combination of diet and physical activity strategies. Primary Aim 2: To examine the role played by social cognitive factors in changing nutrition and physical activity behaviors across one academic year. We hypothesize that self-efficacy will have both a direct influence on behavior and an indirect effect through its influence on self-regulatory skills and outcome expectations.
Behavioral Intervention
Diabetes Genetic Counseling for Obesity
This study will examine the impact diabetes genetic counseling on patient motivation and disease prevention behaviors among subjects with pre-diabetes. Intervention subjects will be provided with their individual diabetes genotype risk score derived from aggregating the combined results of 37 diabetes risk-associated genetic loci. Controls will not be tested. All subjects will be enrolled in a 12-week diabetes prevention program.
Phase 3 Prevention Clinical Trials
View 80 phase 3 prevention medical studies.
Vitamin Supplement
Vitamin D for COVID-19
This trial is testing whether vitamin D supplements can reduce the rate of people seeking healthcare for symptoms related to COVID-19, and whether it can reduce the risk of infection with the virus in people who have been recently diagnosed with COVID-19.
Biguanides
Lifestyle Changes + Metformin for Diabetes Prevention
This trial looks at the ability of an intensive lifestyle or metformin to prevent or delay the development of diabetes in a high risk population. Lifestyle reduced diabetes onset by 58% and metformin reduced diabetes onset by 31%.
Prevention Clinical Trials With No Placebo
View 80 prevention medical studies that do not have a placebo group.
Behavioural Intervention
Risk-Based Screening for Breast Cancer
This trial is comparing annual breast cancer screening to a risk-based breast cancer screening schedule. The goal is to see if the risk-based schedule detects breast cancers earlier and causes fewer false positives.
View More Prevention Trials
See another 52 medical studies focused on prevention.
Frequently Asked Questions
Introduction to prevention
What are the top hospitals conducting prevention research?
When it comes to groundbreaking clinical trials in the field of prevention, several top hospitals across the United States are making notable strides. Brigham and Women's Hospital in Boston leads the way with six active prevention trials aimed at identifying strategies to ward off various diseases. While they have yet to conduct any prevention trials historically, their commitment to preventive medicine is evident. Similarly, Mayo Clinic in Rochester is actively engaged in four ongoing prevention studies, focusing on innovative approaches to disease prevention. Although they also do not have a past record of conducting preventive trials, their dedication towards exploring preventative measures is commendable.
In Aurora, Colorado, Children's Hospital Colorado recognizes the importance of early intervention and has three active prevention trials underway. These efforts aim to identify ways to prevent or mitigate health issues from an early age and support children's well-being as they grow up.
Meanwhile, Dent Neurologic Institute located in Amherst acknowledges that preventing neurological disorders carries immense significance for overall health outcomes. They currently contribute by running three active clinical trials focused on preventive strategies within this realm.
Lastly,nestled away in Bellevue,the Northwest Clinical Research Center signifies its role as a crucial player by hosting three ongoing preventive clinical investigations without prior historical input.Their current endeavors involve pioneering research into preventative measures against various conditions related issues emphasizing their contribution towards ensuring healthier lives
These esteemed institutions demonstrate unwavering commitment toward mitigating risks before diseases surface and promoting overall wellness through proactive approaches.Across different locations these top-tier hospitals exemplify how ongoing collaborative work continues driving us closer than ever before towards cultivating healthier lives for everyone
Which are the best cities for prevention clinical trials?
When it comes to prevention clinical trials, several cities have emerged as leaders in research and development. Boston, Massachusetts leads the way with 18 active trials focusing on interventions like Enteric Coated Aspirin, Deferoxamine, and Vitamin d. New york, New York follows closely behind with 13 ongoing studies examining strategies such as targeted screening advice based on comprehensive risk assessments. Miami, Florida; Phoenix, Arizona; and Baltimore Maryland also contribute significantly to prevention research with their own set of active trials exploring various preventive measures. These cities offer individuals opportunities to participate in cutting-edge clinical trials aimed at preventing diseases and improving overall health outcomes.
Which are the top treatments for prevention being explored in clinical trials?
When it comes to prevention, clinical trials are currently investigating the efficacy of several promising treatments. The top contenders in these trials include:
- Daratumumab: Being tested in multiple ongoing trials
- Belantamab mafodotin: Showing potential as a preventive treatment
- Lenalidomide: Under investigation for its preventive properties
These treatments hold promise for preventing breast cancer and may provide a breakthrough in the fight against this disease. Continued research and development are crucial to improving prevention strategies and ultimately reducing the burden of breast cancer worldwide.
What are the most recent clinical trials for prevention?
Exciting advancements are being made in the realm of prevention, as recent clinical trials offer promising approaches to safeguard against various health conditions. Among these studies is a Phase 2 trial investigating the efficacy of high-dose ORC-13661 for prevention. Additionally, a Phase 3 trial called ReMMiD-C Therapeutic Arm A aims to explore preventive strategies further. Another Phase 3 trial named ROSE (Reach Out, Stay Strong, Essentials) focuses on preventing complications in mothers with newborns. Furthermore, a Phase 2 trial examines the potential benefits of smartphones in preventive measures. Lastly, Stellate ganglion block is being explored through both Phase 2 and Phase 3 trials for its preventative properties. With these innovative initiatives underway, we can anticipate significant progress in disease prevention efforts moving forward.
What prevention clinical trials were recently completed?
Recently, several clinical trials focused on prevention have concluded, providing valuable insights into strategies for disease avoidance. These studies demonstrate the commitment of researchers to proactively addressing health concerns.