VA San Diego Healthcare System, San Diego, CA

Summary

VA San Diego Healthcare System, San Diego, CA is a medical facility located in San Diego, California. This center is recognized for care of Post-Traumatic Stress Disorder, Depression, Schizophrenia, Psychotic Episodes, Traumatic Brain Injury and other specialties. VA San Diego Healthcare System, San Diego, CA is involved with conducting 225 clinical trials across 318 conditions. There are 32 research doctors associated with this hospital, such as Leslie A. Morland, PsyD, Peter Colvonen, MD, Catherine R Ayers, PhD, and Ariel J. Lang, PhD.

Top PIs

Clinical Trials running at VA San Diego Healthcare System, San Diego, CA

Post-Traumatic Stress Disorder

Depression

Bipolar Disorder

Suicide Attempt

Schizophrenia

Psychosis

Insomnia

Clostridium Difficile Infection

Parkinson's Disease

Atherosclerosis

Lorazepam

for PTSD

A substantial majority of Veterans with posttraumatic stress disorder (PTSD) continue to suffer even with the best current medications. Progress in developing more effective medications is hampered by the substantial variability within Veterans with PTSD, meaning the most effective medication likely varies from individual to individual. New scientific tools to help identify distinct subgroups of Veterans with PTSD who are likely to respond to specific medications could help improve treatment in this population. Research has indicated that a specific subgroup of Veterans with PTSD with a high level of anxious arousal may benefit from medications which boost signaling of the neurotransmitter gamma-aminobutyric acid (GABA). This project aims to validate a clinical test to identify these individuals using new computational and neuroimaging methods combined with the medication lorazepam, a positive GABA modulator. The ultimate goal is to use these methods in future clinical trials of new medications to target the best treatments to individual Veterans with PTSD.

Recruiting

2 awards

Phase 4

1 criteria

MDMA-Assisted Therapy

for PTSD

The overall objective of this study is to pilot the VASDHS-adapted Emory MDMA-PE Protocol (aE-MDMA-PE) and assess the effect on clinician-rated PTSD symptoms in veterans who receive different doses of MDMA.

Recruiting

2 awards

Phase 3

10 criteria

Mindfulness Training

for PTSD

This trial compares mindfulness meditation and problem-solving skills classes for Veterans with anxiety, depression, or PTSD. It aims to see which method better reduces symptoms and improves overall functioning in 300 Veterans across various locations. Mindfulness-based stress reduction (MBSR) has been studied extensively and shown to improve PTSD symptoms, depression, and overall well-being in veterans.

Recruiting

1 award

N/A

2 criteria