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Pacific Research Network
Claim this profileSan Diego, California 92103
Global Leader in Alzheimer's Disease
Global Leader in Excessive Daytime Sleepiness
Conducts research for Dementia
Conducts research for Obstructive Sleep Apnea
Conducts research for Narcolepsy
98 reported clinical trials
1 medical researcher
Summary
Pacific Research Network is a medical facility located in San Diego, California. This center is recognized for care of Alzheimer's Disease, Excessive Daytime Sleepiness, Dementia, Obstructive Sleep Apnea, Narcolepsy and other specialties. Pacific Research Network is involved with conducting 98 clinical trials across 46 conditions. There are 1 research doctors associated with this hospital, such as Stephen Thein, MD.Area of expertise
1Alzheimer's Disease
Global LeaderAβ1-42
amyloid PET scan
Aβ1-42 positive
2Excessive Daytime Sleepiness
Global LeaderTop PIs
Clinical Trials running at Pacific Research Network
Alzheimer's Disease
Obstructive Sleep Apnea
Sleep Disorders
Restless Legs Syndrome
Restless Leg Syndrome
Dementia
Psychomotor Agitation
Agitation in Dementia
Menopausal Sleep Disturbances
AVP-786
for Agitation in Alzheimer's Disease
This study is evaluating whether a drug may help reduce the risk of heart attack and stroke in individuals with heart disease.
Recruiting2 awards Phase 37 criteria
Donanemab
for Alzheimer's Disease
This study is evaluating whether a drug called donanemab can slow the progression of Alzheimer's disease.
Recruiting1 award Phase 34 criteria
ABBV-916
for Early Alzheimer's Disease
Alzheimer's disease (AD) is a progressive, irreversible neurological disorder and is the most common cause of dementia in the elderly population. Clinical symptoms of the disease may begin with occasional forgetfulness such as misplacement of items, forgetting important dates or events, and may progress to noticeable memory loss, increased confusion and agitation, and eventually, loss of independence and non-responsiveness. This study will assess how safe and effective ABBV-916 is in treating early AD. Adverse events, change in disease activity, and how ABBV-916 moves through body of participants will be assessed. ABBV-916 is an investigational drug being developed for the treatment of early AD. This study is conducted in 2 stages. Stage A is a multiple ascending dose study. There is a 1 in 4 chance that participants are assigned to receive placebo. Stage B is a proof-of-concept study. In Stage B, there is a 1 in 5 chance that participants will be assigned to receive placebo. The first 6 months of this study are "double-blind," which means that neither the trial participant nor the study doctors know which treatments will be given. This will be followed by a 2-year extension period in which all participants will receive ABBV-916. Approximately 195 participants aged 50-90 years will be enrolled in about 90 sites across the world. Participants will receive intravenous (IV) doses of ABBV-916 or placebo once every 4 weeks (Q4W) for 24 weeks and will be followed for an additional 16 weeks. There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, magnetic resonance imaging (MRI), blood tests, checking for side effects and completing questionnaires.
Recruiting0 awards Phase 26 criteria
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Frequently asked questions
What kind of research happens at Pacific Research Network?
Pacific Research Network is a medical facility located in San Diego, California. This center is recognized for care of Alzheimer's Disease, Excessive Daytime Sleepiness, Dementia, Obstructive Sleep Apnea, Narcolepsy and other specialties. Pacific Research Network is involved with conducting 98 clinical trials across 46 conditions. There are 1 research doctors associated with this hospital, such as Stephen Thein, MD.