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John H. Stroger Jr. Hospital of Cook County

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Chicago, Illinois 60612

Global Leader in HIV Infection

Global Leader in Human Immunodeficiency Virus Infection

Conducts research for Breast Cancer

Conducts research for AIDS

Conducts research for Lung Cancer

369 reported clinical trials

6 medical researchers

Photo of John H. Stroger Jr. Hospital of Cook County in ChicagoPhoto of John H. Stroger Jr. Hospital of Cook County in ChicagoPhoto of John H. Stroger Jr. Hospital of Cook County in Chicago

Summary

John H. Stroger Jr. Hospital of Cook County is a medical facility located in Chicago, Illinois. This center is recognized for care of HIV Infection, Human Immunodeficiency Virus Infection, Breast Cancer, AIDS, Lung Cancer and other specialties. John H. Stroger Jr. Hospital of Cook County is involved with conducting 369 clinical trials across 513 conditions. There are 6 research doctors associated with this hospital, such as Thomas E. Lad, Paul Rubinstein, MD, Lakshmi Rajdev, and Janardhan Mydam, MD.

Area of expertise

1

HIV Infection

Global Leader

John H. Stroger Jr. Hospital of Cook County has run 101 trials for HIV Infection. Some of their research focus areas include:

Stage IV
Stage II
Stage III
2

Human Immunodeficiency Virus Infection

Global Leader

John H. Stroger Jr. Hospital of Cook County has run 86 trials for Human Immunodeficiency Virus Infection.

Top PIs

Clinical Trials running at John H. Stroger Jr. Hospital of Cook County

Lung Cancer

Ovarian Cancer

Breast Cancer

Cancer

Breast cancer

Esophageal cancer

Colorectal Cancer

Pancreatic Cancer

Prostate Cancer

Multiple Myeloma

Image of trial facility.

Treatment Timing

for Non-Small Cell Lung Cancer

This phase III trial compares standard therapy given after surgery (adjuvant) to standard therapy given before and after surgery (perioperative) in treating patients with stage II-IIIB non-small cell lung cancer (NSCLC) that can be removed by surgery (resectable). The usual approach for patients with resectable NSCLC is chemotherapy and/or immunotherapy before surgery, after surgery, or both before and after surgery. This study is being done to find out which approach is better at treating patients with lung cancer. Treatment will be administered according to the current standard of care at the time of enrollment. Chemotherapy options may include cisplatin, carboplatin, pemetrexed, gemcitabine, docetaxel, and vinorelbine at standard doses according to the treating physician. Cisplatin is in a class of medications known as platinum-containing compounds. It works by killing, stopping or slowing the growth of tumor cells. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Pemetrexed is in a class of medications called antifolate antineoplastic agents. It works by stopping cells from using folic acid to make deoxyribonucleic acid (DNA) and may kill tumor cells. Gemcitabine is a chemotherapy drug that blocks the cells from making DNA and may kill tumor cells. Docetaxel is in a class of medications called taxanes. It stops tumor cells from growing and dividing and may kill them. Other chemotherapy drugs, such as vinorelbine, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading . Immunotherapy with monoclonal antibodies, such as nivolumab, pembrolizumab, and atezolizumab, may help the body's immune system attack the tumor, and may interfere with the ability of tumor cells to grow and spread. Starting treatment with chemotherapy and immunotherapy prior to surgery and continuing treatment after surgery may be a more effective treatment option than adjuvant therapy alone in patients with stage II-IIIB resectable NSCLC.

Recruiting

2 awards

Phase 3

4 criteria

Image of trial facility.

Immunotherapy + Chemotherapy

for Non-Small Cell Lung Cancer

This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.

Recruiting

2 awards

Phase 3

27 criteria

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Blood Sample Collection

for Cancer Detection

This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in the laboratory may help researchers develop tests for the early detection of cancers.

Recruiting

1 award

N/A

9 criteria

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