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Duke University Medical Center

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Durham, North Carolina 27701

Global Leader in Cancer

Global Leader in Breast Cancer

Conducts research for Lung Cancer

Conducts research for Heart Failure

Conducts research for Prostate Cancer

2976 reported clinical trials

271 medical researchers

Photo of Duke University Medical Center in DurhamPhoto of Duke University Medical Center in Durham

Summary

Duke University Medical Center is a medical facility located in Durham, North Carolina. This center is recognized for care of Cancer, Breast Cancer, Lung Cancer, Heart Failure, Prostate Cancer and other specialties. Duke University Medical Center is involved with conducting 2,976 clinical trials across 2,908 conditions. There are 271 research doctors associated with this hospital, such as Lars Wagner, MD, Jessica M. Sun, Jeffrey Crawford, and Angeles A. Secord.

Area of expertise

1

Cancer

Global Leader

Duke University Medical Center has run 241 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage I
2

Breast Cancer

Global Leader

Duke University Medical Center has run 161 trials for Breast Cancer. Some of their research focus areas include:

Stage IV
ER positive
HER2 negative

Top PIs

Clinical Trials running at Duke University Medical Center

Lung Cancer

Skin Cancer

Breast Cancer

Ovarian Cancer

Testicular cancer

Multiple Myeloma

Chronic Lymphocytic Leukemia

Cancer

Multiple Sclerosis

Prostate Cancer

Image of trial facility.

Sotorasib Combo vs Pembrolizumab Combo

for Advanced Lung Cancer

This trial is testing two different drug combinations with chemotherapy to see which helps cancer patients live longer without their disease getting worse. One combination includes sotorasib, which targets cancer mutations, and the other includes pembrolizumab, which helps the immune system fight cancer. Pembrolizumab has been shown to improve overall survival in various cancers when combined with chemotherapy.

Recruiting

2 awards

Phase 3

3 criteria

Image of trial facility.

High-Dose Radiation + Chemotherapy and Immunotherapy

for Non-Small Cell Lung Cancer

This trial tests whether adding a precise form of radiation therapy to the usual treatment improves outcomes for patients with advanced lung cancer that can't be operated on. The goal is to see if this combination helps patients live longer and prevents cancer from worsening. This form of radiation therapy has shown promise in improving survival rates in patients with various stages of lung cancer.

Recruiting

2 awards

Phase 3

14 criteria

Image of trial facility.

Immunotherapy + Chemotherapy

for Non-Small Cell Lung Cancer

This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.

Recruiting

2 awards

Phase 3

27 criteria

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Frequently asked questions

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