Cohen Children's Medical Center

Summary

Cohen Children's Medical Center is a medical facility located in New Hyde Park, New York. This center is recognized for care of Solid Tumors, Sickle Cell Disease, Still's Disease, Cancer, Cystic Fibrosis and other specialties. Cohen Children's Medical Center is involved with conducting 57 clinical trials across 167 conditions. There are 16 research doctors associated with this hospital, such as Julie Krystal, Matthew Taylor, MD, Carolyn F. Levy, and Marina Frimer, MD.

Top PIs

Clinical Trials running at Cohen Children's Medical Center

Focal Segmental Glomerulosclerosis

Cardiac Arrest

Rheumatoid Arthritis

Lipoid Nephrosis

Nephrotic syndrome

Cystic Fibrosis

Acute Respiratory Distress Syndrome

Vocal Cord Paralysis

Polycystic Kidney Disease

IgA Nephropathy

Sparsentan

for Proteinuric Kidney Disease

This trial is testing sparsentan, a daily oral medication, in children with specific kidney diseases that cause high protein levels in urine. The goal is to see if it is safe and effective. Sparsentan helps by reducing protein leakage into the urine, which can protect the kidneys.

Recruiting

1 award

Phase 2

10 criteria

Vagus Nerve Stimulation

for Nephrotic Syndrome

Children with steroid resistant nephrotic syndrome (SRNS) are exposed to prolonged courses of immunosuppressant medications. Given the adverse side effect profiles and variable efficacy of these medications, there is an urgent need to identify novel and safe therapies to treat nephrotic syndrome in children. Stimulation of the vagus nerve, which can be activated noninvasively by transcutaneous auricular vagus nerve stimulation (taVNS), has immunomodulatory effects mediated by the inflammatory reflex and spleen. taVNS has become a therapy of interest for treating chronic immune mediated illnesses. The aims of the study are (1) To determine the feasibility of protocol implementation and tolerability of taVNS in the treatment of nephrotic syndrome in children (2) To establish proof-of-concept and generate statistical estimates of variance parameters and effect sizes for treatment response outcomes in children with nephrotic syndrome randomized to taVNS therapy compared with sham therapy (3) To investigate the effects of taVNS on inflammatory markers in children with nephrotic syndrome.

Recruiting

0 awards

N/A

9 criteria

taVNS

for Nephrotic Syndrome in Children

This trial tests a new treatment for children with frequently relapsing nephrotic syndrome using a device that sends gentle electrical pulses to the ear. The goal is to see if this method can safely help manage their condition by reducing inflammation through nerve stimulation.

Recruiting

0 awards

N/A

6 criteria