Advancing Treatments for Cystic Fibrosis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to gather important health data from people with cystic fibrosis (CF) who do not use CFTR modulators, which are specific medications for CF. This information will help researchers design better treatments and trials for those who can't or don't take these modulators. The trial also seeks to engage participants in CF research and educate them about what it involves. It suits individuals diagnosed with CF who haven't recently used CFTR modulators or new therapies.
As an unphased trial, this study offers participants the chance to contribute to the foundational understanding of CF and influence future treatment options.
Why are researchers excited about this trial?
Researchers are excited about these treatments for cystic fibrosis (CF) because they aim to help people who can't benefit from current modulators. Unlike existing CF treatments that work by improving the function of faulty CFTR proteins, these new therapies focus on bypassing the need for CFTR modulators altogether. They target the underlying genetic causes of CF, offering hope for patients who previously had limited options. This approach could significantly broaden the reach of effective CF therapies, potentially improving quality of life for many.
Who Is on the Research Team?
Scott Donaldson, MD
Principal Investigator
University of North Carolina, Chapel Hill
Felix Ratjen, MD
Principal Investigator
University of Toronto
Deepika Polineni, MD, MPH
Principal Investigator
Washington University School of Medicine
Nicole Mayer-Hamblett, PhD
Principal Investigator
Seattle Children's Hospital
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Observational Data Collection
Participants' health data and specimens are collected for research purposes
Follow-up
Participants are monitored for safety and effectiveness after data collection
What Are the Treatments Tested in This Trial?
Find a Clinic Near You
Who Is Running the Clinical Trial?
Nicole Hamblett
Lead Sponsor
University of North Carolina, Chapel Hill
Collaborator
Washington University School of Medicine
Collaborator
University of Toronto
Collaborator
Cystic Fibrosis Foundation
Collaborator
Florida State University
Collaborator
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.