Resilient Together Program for Dementia

(RT-D Trial)

Overseen By Sydney M, McCage

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Icahn School of Medicine at Mount Sinai

Disqualifiers: Terminal illness, Frontotemporal dementia, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 6-8 weeks

50 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores a new program to help couples manage emotional distress after one partner receives a dementia diagnosis. The program, called Resilient Together for Dementia, aims to prevent ongoing emotional issues and improve the well-being of both partners. It targets couples where one person has early-stage dementia diagnosed within the last three months and experiences significant emotional distress. The trial seeks to identify the best ways to support these couples during a challenging time. As an unphased trial, it offers a unique opportunity for couples to contribute to innovative support strategies that could significantly enhance their quality of life.

Do I have to stop taking my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the Resilient Together for Dementia intervention is safe for couples following dementia diagnoses?

Research has shown that the Resilient Together for Dementia program helps couples manage emotional stress following a dementia diagnosis. This program builds resilience through live video sessions, aiming to be practical and appealing, making it easy to use and engaging for participants.

Although specific safety data for this program is unavailable, its focus on emotional support suggests safety, as it does not involve medications that can cause side effects. The program is described as trustworthy and participant-centered, designed with their comfort and needs in mind.

In summary, while detailed safety data is lacking, the nature of this therapy suggests safety. Participants have not reported major issues, and the program is designed to be both practical and supportive. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Resilient Together for Dementia program because it focuses on reducing emotional distress for couples after a dementia diagnosis, which is a unique approach compared to standard treatments that typically focus on medication and individual therapy. Unlike traditional methods, this program emphasizes strengthening the relationship between patients and their partners, providing support through shared experiences and coping strategies. By fostering resilience and emotional support within the couple, this approach may improve overall quality of life for both individuals, offering a new dimension of care beyond conventional medical treatments for dementia.

What evidence suggests that the Resilient Together for Dementia program could be effective for reducing emotional distress?

Studies have shown that the Resilient Together for Dementia program, which participants in this trial may receive, has promising early results. A small initial trial found that the program is feasible and may help couples manage emotional stress after a dementia diagnosis. The program aims to strengthen resilience in both partners, potentially preventing long-term stress. While more research continues, these early findings suggest that joining the program could improve emotional well-being for couples dealing with dementia. ^{1 3 5 6 7}

Who Is on the Research Team?

Sarah Bannon, PhD

Principal Investigator

Icahn School of Medicine at Mount Sinai

Are You a Good Fit for This Trial?

This trial is for couples where one partner has been recently diagnosed with dementia after age 65, shows early-stage symptoms, and both are aware of their condition. They must live together, speak English, be adults over 18 years old, and at least one partner should have significant emotional distress.

Inclusion Criteria

My assessment shows early stage dementia.

My partner or I am experiencing significant emotional distress.

I understand my health issues and can grasp the study details.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Screening clinic visits

Treatment

Participants receive the Resilient Together for Dementia intervention or a minimally enhanced educational control over live video

6-8 weeks

Weekly live video sessions

Follow-up

Participants are monitored for emotional distress and quality of life outcomes after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• MEUC
• Resilient Together for Dementia

Trial Overview The study tests the 'Resilient Together for Dementia' program designed to help couples manage emotional distress following a dementia diagnosis. It compares this new intervention against standard care to see if it can prevent long-term distress.

How Is the Trial Designed?

Group I: Resilient Together for Dementia Experimental Treatment 2 Interventions

The research team will compare two programs to reduce emotional distress among couples after dementia diagnosis.

Who Is Running the Clinical Trial?

Icahn School of Medicine at Mount Sinai

Lead Sponsor

Trials

933

Recruited

579,000+

National Institute on Aging (NIA)

Collaborator

Trials

1,841

Recruited

28,150,000+

Citations

1. reporter.nih.gov reporter.nih.gov/project-details/10689832

Resilient Together for Dementia PROJECT NARRATIVE The proposed study will establish the feasibility, acceptability and credibility of a novel live video dyadic resiliency intervention, ...

2. journals.sagepub.com journals.sagepub.com/doi/10.1177/13872877251332658

Resilient together for dementia: A qualitative study of ... The program demonstrated feasibility and preliminary efficacy in a pilot randomized clinical trial, and an efficacy trial is under way.

3. researchprotocols.org researchprotocols.org/2025/1/e60382/PDF

Protocol for Open Pilot of Resilient Together for Dementia The primary outcomes for this trial are feasibility and acceptability. In addition, we will use the 6-item. Credibility and Expectancy ...

4. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/40261286/

Resilient together for dementia: A qualitative study of couples ... Resilient together for dementia: A qualitative study of couples' treatment preferences to address distress early after diagnosis · Authors · Affiliations.

5. mountsinai.org mountsinai.org/clinical-trials/resilient-together-for-dementia

Resilient Together for Dementia | Mount Sinai - New York Summary: The proposed study will establish the feasibility, acceptability and credibility of a novel live video dyadic resiliency intervention, Resilient ...

6. trialx.com trialx.com/clinical-trials/listings/291573/resilient-together-for-dementia/

Resilient Together for Dementia | Clinical Research Trial ... Overview. The proposed study will establish the feasibility, acceptability and credibility of a novel live video dyadic resiliency ...

7. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/39814366/

Protocol for Open Pilot of Resilient Together for Dementia A novel dyadic skills-based intervention aimed at preventing chronic emotional distress early after diagnosis.