Brief Prolonged Exposure Therapy for Post-Traumatic Stress Disorder

Recruiting at 2 trial locations

Overseen By Jessica Rostockyj, M.S

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Baylor Research Institute

Disqualifiers: Police custody, Non-English, Cognitive impairment, Suicidal, Psychosis

Compensation: Varies

Number of Visits: 6

Duration: 3 weeks

300 Participants Needed

Trial Summary

What is the purpose of this trial?

The purpose of this research is to determine if a brief treatment method is effective for preventing posttraumatic stress disorder (PTSD) and a number of other concerns following injury.

Research Team

Ann Marie Warren, PhD

Principal Investigator

Baylor Scott & White Research Institute

Eligibility Criteria

This trial is for individuals admitted to specific Level I Trauma Centers after an injury, who may be at risk of developing PTSD. It's not open to those with certain conditions that could interfere with the study or their recovery.

Inclusion Criteria

You were admitted to one of these specific hospitals for trauma care.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive Brief Prolonged Exposure Therapy, consisting of three 60-minute sessions

3 weeks

3 visits (in-person)

Follow-up

Participants are monitored for PTSD symptoms and other health outcomes at 1, 3, and 6 months from baseline

6 months

3 visits (in-person)

Treatment Details

Interventions

• Brief Prolonged Exposure Therapy

Trial Overview Researchers are testing a short therapy called Brief Prolonged Exposure Therapy against the usual treatment methods to see if it can prevent PTSD following traumatic injuries.

Participant Groups

Group I: Brief Prolonged Exposure Experimental Treatment 1 Intervention

Participants in the experimental group will receive Brief Prolonged Exposure Therapy. In addition to the standard clinical treatment received by all patients at BUMC, BSWMC Temple and FH/MCW (treatment as usual), participants randomized to the intervention condition will also receive three 60-minute sessions of Brief PE. Participants in the BPE group will complete a screener and then questionnaires/interviews at 1, 2, and 6 months from Baseline.

Group II: Treatment as Usual Placebo Group 1 Intervention

Participants in the Treatment as Usual group (TAU) will not receive the Brief PE therapy, but the standard clinical treatment received by all patients admitted to BUMC, BSWMC Temple or FH/MCW trauma centers. Treatment as usual participants will have follow-up assessments at 1, 3, and 6 months from Baseline.

Who Is Running the Clinical Trial?

Baylor Research Institute

Lead Sponsor

Trials

210

Recruited

205,000+

Froedtert Hospital

Collaborator

Trials

10

Recruited

10,700+

Medical College of Wisconsin

Collaborator

Trials

645

Recruited

1,180,000+