Vision Training for Low Vision
(FLAP Trial)
Trial Summary
What is the purpose of this trial?
A greater understanding of plasticity after central vision loss can inform new therapies for treating low vision and has the potential to benefit millions of individuals suffering from low vision. The treatment of low vision is particularly relevant to the mission of the National Eye Institute (NEI) to support research on visual disorders, mechanisms of visual function, and preservation of sight. The comparison of different training and outcome factors is in line with the National Institute of Mental Health (NIMH) Research Domain Criteria (RDOC) framework and studies in an aging population are consistent with the mission of the National Institute on Aging (NIA).
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment for Vision Training for Low Vision?
Research shows that low vision rehabilitation, which includes visual training and other methods, can improve the quality of life for individuals with low vision by helping them use their remaining vision more effectively. This approach is personalized and involves a multidisciplinary team to enhance visual functioning and independence.12345
Is vision training for low vision generally safe for humans?
How does the Vision Training for Low Vision treatment differ from other treatments for low vision?
This treatment is unique because it focuses on training various aspects of vision, such as spatial attention and visual sensitivity, to enhance the brain's ability to adapt to visual impairment. Unlike standard treatments that may rely on devices or aids, this approach leverages the brain's plasticity (ability to change and adapt) to improve visual performance and quality of life.23456
Eligibility Criteria
This trial is for individuals aged 18-30 with corrected vision of 20/40 or better and no retinal pathology. It's not suitable for those needing special glasses, over certain body size limits, pregnant, with pacemakers/metal implants (except some dental work), weighing over 300 pounds, claustrophobic, hearing-impaired, with extensive tattoos near the head, a history of serious head injury or hallucinations/delusions.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Training
Participants undergo training in visual sensitivity, spatial integration, and spatial attention over a 7-week period.
Follow-up
Participants are monitored for changes in visual and neural metrics after training completion.
Treatment Details
Interventions
- Combination training
- Training spatial attention
- Training spatial integration
- Training visual sensitivity
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alabama at Birmingham
Lead Sponsor
University of California, Riverside
Collaborator