6000 Participants Needed

Videos for Vaccinations

MG
Overseen ByMichelle Goryn
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Johns Hopkins Bloomberg School of Public Health
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to determine which type of video content—informational animations, personal stories, or a mix of both—most effectively encourages older adults to get vaccinated. Researchers will divide participants into groups to watch different video types or none at all. The trial targets U.S. adults aged 50 and older who can watch videos on their devices. As an unphased trial, it offers participants the chance to contribute to important research that could enhance public health messaging for older adults.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that these video interventions are safe for increasing vaccination rates among older adults?

Research has shown that both animated and personal story videos are safe and well-received. Studies have found that animated videos can improve perceptions of vaccines without causing negative effects. For instance, a study with over 4,000 participants found these videos enhanced understanding of vaccines, with no reported issues.

Similarly, personal story videos have increased confidence in vaccines. Research found that viewers considered these videos helpful and easy to understand, with no reports of harm. This suggests that both types of videos are safe ways to share vaccine information.12345

Why are researchers excited about this trial?

Researchers are excited about the "Videos for Vaccinations" trial because it explores innovative ways to improve vaccine uptake through the power of video storytelling. Unlike traditional methods that rely on written information or direct healthcare provider communication, this trial evaluates how different video formats—informational animations and personal narratives—impact people's decision to get vaccinated. The unique approach combines educational content with engaging personal stories, potentially making vaccine information more relatable and easier to understand. By testing different combinations, such as narrative followed by animation or vice versa, researchers aim to discover the most effective way to influence and motivate people to choose vaccination.

What evidence suggests that this trial's video interventions could be effective in increasing vaccination among older adults?

Research has shown that informational videos can change how people think about vaccines. One study found that 4,076 out of 7,090 unvaccinated individuals chose to get vaccinated after watching videos explaining mRNA vaccines. These videos simplify complex ideas, boosting confidence in vaccination.

In this trial, participants will watch different types of video content. Some will view an informational animation, while others will see a personal narrative video. Videos sharing personal stories are effective because they make information relatable and can improve attitudes toward vaccines. Another study demonstrated that these stories help people understand and overcome vaccine hesitancy, which refers to doubt or fear about vaccines. Both types of videos have increased interest in vaccines, making them promising tools for boosting vaccination rates.14678

Who Is on the Research Team?

DS

Daniel Salmon, PhD

Principal Investigator

Johns Hopkins University

Are You a Good Fit for This Trial?

This trial is for U.S. adults aged 50 and older who are interested in learning about vaccinations through videos. The study aims to find out if certain types of videos can encourage them to get vaccinated.

Inclusion Criteria

I am 50 years old or older and live in the U.S.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants view different combinations of informational and personal narrative videos to assess their impact on vaccination uptake

4-6 weeks

Follow-up

Participants are monitored for vaccination status and effectiveness of the video interventions

9 months

What Are the Treatments Tested in This Trial?

Interventions

  • Informational Animation Video
  • Personal Narrative Video
Trial Overview The study is testing the effectiveness of different video types on vaccine uptake among older adults: informational animation videos, personal narrative videos, and a combination of both.
How Is the Trial Designed?
5Treatment groups
Experimental Treatment
Active Control
Group I: Narrative Then AnimationExperimental Treatment2 Interventions
Group II: Narrative OnlyExperimental Treatment1 Intervention
Group III: Animation Then NarrativeExperimental Treatment2 Interventions
Group IV: Animation OnlyExperimental Treatment1 Intervention
Group V: ControlActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Johns Hopkins Bloomberg School of Public Health

Lead Sponsor

Trials
441
Recruited
2,157,000+

Merck Sharp & Dohme LLC

Industry Sponsor

Trials
4,096
Recruited
5,232,000+
Chirfi Guindo profile image

Chirfi Guindo

Merck Sharp & Dohme LLC

Chief Marketing Officer since 2022

Degree in Engineering from Ecole Centrale de Paris, MBA from New York University Stern School of Business

Robert M. Davis profile image

Robert M. Davis

Merck Sharp & Dohme LLC

Chief Executive Officer since 2021

JD from Northwestern University Pritzker School of Law, MBA from Northwestern University Kellogg Graduate School of Management, Bachelor's in Finance from Miami University

Citations

Effect of informational videos on vaccine perceptions ...This study, involving 4076 out of 7090 unvaccinated individuals, shows that providing information on (1) how mRNA vaccines work, (2) how the ...
Evaluating the impact of short animated videos on COVID ...SAS videos influenced determinants of vaccination behavior, thus indirectly affecting vaccination uptake. Abstract. Addressing the global challenge of vaccine ...
Effects of Scalable, Wordless, Short, Animated Storytelling ...The vaccination prevents infection, but widespread vaccine hesitancy remains a significant barrier. Short, animated storytelling videos may help ...
The effect of a short, animated story-based video on COVID ...We designed a collage of three short, animated story-based (SAS) videos to convey scientifically informed and accessible information about COVID-19 vaccine.
A randomized controlled trial of a video intervention shows ...This study examines an eight-minute, animated, educational YouTube video on the COVID-19 mRNA vaccines that we made called “COVID mRNA vaccines ...
Evaluating the impact of short animated videos on COVID-19 ...Evaluating the impact of short animated videos on COVID-19 vaccine hesitancy: An online randomized controlled trial
Effects of Scalable, Wordless, Short, Animated Storytelling ...The vaccination prevents infection, but widespread vaccine hesitancy remains a significant barrier. Short, animated storytelling videos may help ...
Animated, video entertainment-education to improve vaccine ...To improve vaccine confidence, we designed three short, animated videos employing three research-informed pedagogical strategies.
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