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Tamsulosin for Postoperative Urinary Retention

Phase < 1
Recruiting
Led By Thomas Bauer, MD
Research Sponsored by Hackensack Meridian Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Planned thoracic oncological surgical procedure of a video assisted oncological surgical procedure for suspected or confirmed cancer.
Surgery scheduled more than 7 days from the time of consent
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 6-8 hours post operative
Awards & highlights

Study Summary

This trial will test if Tamsulosin can reduce the risk of post-surgery urinary retention in older men with cancer surgery. It will also look at how quickly normal urinary function returns.

Who is the study for?
This trial is for men aged 55 or older who are scheduled to have thoracic cancer surgery and haven't used Tamsulosin before. They shouldn't have low blood pressure, a history of heart failure, valvular heart disease, or previous prostate surgery.Check my eligibility
What is being tested?
The study tests if Tamsulosin can reduce the high rates of urinary retention after thoracic cancer surgery in older men and how quickly it helps resume normal urinary function post-surgery.See study design
What are the potential side effects?
Tamsulosin may cause dizziness, especially when standing up from sitting or lying down (orthostatic hypotension), allergies in those sensitive to sulfa drugs, and could interact with certain medications like Boceprevir.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am scheduled for a minimally invasive chest cancer surgery.
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My surgery is scheduled for more than a week after I give consent.
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I am a man aged 55 or older.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~6-8 hours post operative
This trial's timeline: 3 weeks for screening, Varies for treatment, and 6-8 hours post operative for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Amount of residual urine
Number of participants that needed an intervention due to failure to spontaneously urinate
Number of participants that were able to spontaneously void after surgery completion
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: Pre-operative Tamsulosin administrationExperimental Treatment1 Intervention
Subjects will be provided with a prescription for Tamsulosin (generic) to be taken 7 days prior to scheduled surgery for thoracic cancer. Tamsulosin dose is set at 0.4mg/day and should be taken daily for seven days prior to their planned surgery date. Study subjects will also be given a diary to record their daily usage. Study subjects should take Tamsulosin on the day of the surgery with a sip of water.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tamsulosin
2002
Completed Phase 4
~16790

Find a Location

Who is running the clinical trial?

Hackensack Meridian HealthLead Sponsor
131 Previous Clinical Trials
28,198 Total Patients Enrolled
1 Trials studying Urinary Retention
127 Patients Enrolled for Urinary Retention
Thomas Bauer, MDPrincipal InvestigatorHackensack Meridian Health
1 Previous Clinical Trials
128 Total Patients Enrolled

Media Library

Pre-operative Tamsulosin administration Clinical Trial Eligibility Overview. Trial Name: NCT05657990 — Phase < 1
Urinary Retention Research Study Groups: Pre-operative Tamsulosin administration
Urinary Retention Clinical Trial 2023: Pre-operative Tamsulosin administration Highlights & Side Effects. Trial Name: NCT05657990 — Phase < 1
Pre-operative Tamsulosin administration 2023 Treatment Timeline for Medical Study. Trial Name: NCT05657990 — Phase < 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research endeavor currently inviting participants?

"Evidently, the trial mentioned is not accepting patient enrollment at this juncture. This clinical study was published on December 20th 2023 and last modified on December 12th 2022. However, 32 additional trials are presently seeking participants to join their respective studies."

Answered by AI
~31 spots leftby Dec 2026