Home-Based Physical Activity for Bladder Cancer

(EMPOWER Trial)

Overseen By Sarah Psutka, MD, MSc

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Washington

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

What You Need to Know Before You Apply

What is the purpose of this trial?

This clinical trial compares how well a home-based personalized physical activity program (PAP) that is delivered by a digital application (app) (the ExerciseRx app) works compared to health education in improving physical activity for patients with bladder cancer that has not reached the muscle wall of the bladder (non-muscle invasive). For people who are not physically active, previous studies have shown that increasing step counts can reduce incidence of death, reduce frailty, and reduce healthcare costs. The ExerciseRx app tracks adherence to home exercise, adapts step count goals based on the patient's progress, and provides encouraging feedback and motivation from the healthcare team. Additional features include activity summaries, progress towards current goal, nudges, helpful facts about the benefits of activity, and ideas for how to incorporate daily movement. A home-based PAP using the ExerciseRx app may work better in increasing physical activity among patients with non-muscle invasive bladder cancer compared to a health education only group.

Who Is on the Research Team?

Sarah Psutka, MD, MSc

Principal Investigator

Fred Hutch/University of Washington Cancer Consortium

Are You a Good Fit for This Trial?

This trial is for patients with non-muscle invasive bladder cancer who are not very active. It's to see if a home-based exercise program using an app can improve their physical activity compared to just getting health education.

Inclusion Criteria

I am 18 years old or older.

I have had bladder cancer that was not muscle-invasive and am currently under surveillance or receiving maintenance therapy.

Classified as insufficiently active on the Physical Activity as a Vital Sign (PAVS) assessment

Exclusion Criteria

Not receiving treatment at University of Washington (UW)

Inability to read or understand English

Lack of access or lack of sufficient facility to use an Android or iOS smart device with the minimum criteria to run the ExerciseRx app

What Are the Treatments Tested in This Trial?

Interventions

• Home-Based Physical Activity Program with Digital App

Trial Overview

The study tests a digital app called ExerciseRx, designed to increase physical activity through personalized step count goals and motivational feedback, against standard health education for inactive bladder cancer patients.

How Is the Trial Designed?

Group I: Group II: Physical Activity Program (PAP) intervention Experimental Treatment 7 Interventions

Patients complete home exercise sessions given via the ExerciseRx app over 20-30 minutes 4 times per week for 12 weeks and receive daily step count goals. Patients also receive a FitBit® to wear continuously throughout the study, and are given access to view their step counts via the ExerciseRx app, and receive an educational pamphlet as in Group I.

Group II: Group I: Health Education Group (HEG) Active Control 7 Interventions

Patients receive recommendations from their physicians to continue their usual physical activity as tolerated, receive a FitBit® to wear continuously throughout the study, with the ExerciseRx app locked to the baseline home screen, and receive an educational pamphlet describing physical activity goals in line with NCCN Survivorship for Healthy Living Guidelines.

Who Is Running the Clinical Trial?

University of Washington

Lead Sponsor

Trials

1,858

Recruited

2,023,000+

Andy Hill CARE Fund

Collaborator