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Tic Suppression Task for Tourette Syndrome (NS in TS Trial)

N/A

Waitlist Available

Led By Marco Bortolato, MD PhD

Research Sponsored by University of Utah

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up through study completion, an average of 2 years

Awards & highlights

NS in TS Trial Summary

This trial will explore the endocrine mechanisms underlying Tourette syndrome, with the goal of identifying potential biomarkers and therapeutic targets.

Who is the study for?

This trial is for boys and girls aged 8-12 with Tourette Syndrome (TS), who can perform a tic suppression task. Participants must meet the diagnostic criteria for TS, have no other tic disorders if they are controls, and be at a certain stage of puberty. Those with major psychiatric or neurological disorders, endocrine issues, or on hormone-altering drugs cannot join.Check my eligibility

What is being tested?

The study aims to understand why more males have TS and why stress affects it by looking at steroid levels in affected children. It will involve performing a tic suppression task to see how steroids might influence tics.See study design

What are the potential side effects?

Since this trial involves observational tasks rather than medication administration, there are no direct side effects from interventions like drugs; however, participants may experience stress or discomfort during the tasks.

NS in TS Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ through study completion, an average of 2 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~through study completion, an average of 2 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, an average of 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Salivary allopregnanolone concentrations

Secondary outcome measures

Tic frequency

Other outcome measures

Measurement of salivary concentrations of other neuroactive steroids

NS in TS Trial Design

1Treatment groups

Experimental Treatment

Group I: Tic suppressionExperimental Treatment1 Intervention

Children with tics will undergo a tic suppression experimental paradigm.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of UtahLead Sponsor

1,095 Previous Clinical Trials

1,775,465 Total Patients Enrolled

5 Trials studying Tourette Syndrome

360 Patients Enrolled for Tourette Syndrome

University of MiamiOTHER

898 Previous Clinical Trials

409,531 Total Patients Enrolled

Albert Einstein College of MedicineOTHER

286 Previous Clinical Trials

11,856,861 Total Patients Enrolled

Media Library

Tic suppression task Clinical Trial Eligibility Overview. Trial Name: NCT05281445 — N/A

Tourette Syndrome Research Study Groups: Tic suppression

Tourette Syndrome Clinical Trial 2023: Tic suppression task Highlights & Side Effects. Trial Name: NCT05281445 — N/A

Tic suppression task 2023 Treatment Timeline for Medical Study. Trial Name: NCT05281445 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research endeavor encompass any participants aged 20 and over?

"This medical trial is recruiting patients aged 8 to 12. The online database lists 382 studies for minors and 990 clinical trials targeting seniors."

Answered by AI

Is it possible for individuals to join this experiment as participants?

"As documented on clinicaltrials.gov, the application window for this research has closed since it was last updated in mid-March of 2022. However, there are 1,398 other medical studies presently seeking participants."

Answered by AI

Am I eligible to participate in this investigation?

"The trial is searching for 120 children with Tourette syndrome aged between 8 and 12, who qualify according to the following criteria: parental or self-reported Tanner stage of pubic hair development, age range fit for tic suppressions tasks, diagnostic evidence of TS in cases."

Answered by AI