Observational Study for Tooth Extraction Site Healing
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores changes in the jawbone immediately after tooth extraction and their impact on bone healing over four months. It examines whether the bone widens or remains the same after tooth removal and how this might predict the bone's future width and height. Suitable participants have healthy gums, are scheduled for a single tooth extraction with bone grafting (a procedure to promote new bone growth), and have intact surrounding teeth.
As an unphased study, this trial allows participants to contribute to foundational research that could enhance future dental procedures.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is there any evidence suggesting that this trial's treatments are likely to be safe?
Previous studies have shown promising safety results for treatments that expand the area where a tooth was removed. For molar sites, one study found that implants placed immediately after tooth removal had a high success rate of 96.6% after one year, suggesting the procedure is quite safe. Research on non-molar sites also supports this. Studies have shown that specific techniques to preserve the ridge (the bone that holds teeth) can be effective, providing strong evidence that these treatments are generally well-tolerated.
The studies report no significant negative effects, which is a positive sign for safety. As with any medical procedure, individual responses may vary. Overall, these findings indicate that the treatments used in the trial are likely safe for participants.12345Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover what influences bone changes after tooth extractions, which is crucial for better dental restoration outcomes. Unlike current practices that generally focus on techniques to preserve bone after extraction, this study is exploring if immediate changes in bone width occur naturally in some cases. By understanding these natural variations, the findings could lead to more tailored and effective treatments for preserving the alveolar ridge, potentially improving dental implant success rates. This research could redefine the approach to post-extraction care by highlighting the factors that naturally promote bone expansion or stability, offering new insights into optimizing dental treatments.
What evidence suggests that this trial's treatments could be effective for post-extraction ridge changes?
This trial will compare different approaches to alveolar ridge preservation (ARP) after tooth extraction. Research has shown that ARP effectively reduces bone loss following tooth removal. This method stabilizes the bone structure, which is particularly beneficial for future dental implants. In this trial, some participants will undergo immediate post-extraction ridge expansion at molar sites, while others will experience no immediate ridge width change. Similar comparisons will be made for non-molar teeth. Although results can vary, studies suggest that ARP benefits both molar and non-molar tooth removal sites.46789
Who Is on the Research Team?
Vrisiis Kofina, DDS, MS
Principal Investigator
Marquette University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo tooth extraction, bone graft, and resorbable membrane placement
Follow-up
Participants are monitored for changes in buccolingual ridge width and height
What Are the Treatments Tested in This Trial?
Interventions
- Alveolar Ridge Preservation
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Non-molar sites without a change in buccolingual bone width immediately after tooth extraction compared to pre-extraction.
Non-molar sites with an increase of buccolingual bone width immediately after tooth extraction compared to pre-extraction.
Molar sites without a change in buccolingual bone width immediately after tooth extraction compared to pre-extraction.
Molar sites with an increase of buccolingual bone width immediately after tooth extraction compared to pre-extraction.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Marquette University
Lead Sponsor
Citations
Effect of Alveolar Ridge Preservation after Tooth Extraction
We found that alveolar ridge preservation is effective in limiting physiologic ridge reduction as compared with tooth extraction alone.
Long‐term outcomes of post‐extraction alveolar ridge ...
Despite limited evidence, ARP and ARR appear to support favorable long-term outcomes, particularly in implant survival and bone stability.
Efficacy of Alveolar Ridge Preservation in Periodontally ...
Four studies reported healing results at 6 months [2,33,37,40], and one study reported healing results at 4 months [39]. Four studies reported ...
Review ALVEOLAR RIDGE PRESERVATION AT MOLAR ...
Primary outcomes were changes in alveolar ridge width and height. Secondary outcomes included sinus pneumatization and need for additional augmentation at the ...
5.
researchgate.net
researchgate.net/publication/286292841_Immediate_effects_of_tooth_extraction_on_ridge_integrity_and_dimensionsImmediate effects of tooth extraction on ridge integrity and ...
Following extraction, ridge width was expanded in 30 (57 %), collapsed in 12 (23 %), and remained unchanged in 11 (21 %) sites. In most sites ( ...
Bone Stability After Immediate Implants and Alveolar Ridge ...
The study examined bone levels and implant survival over time, using standardized intraoral radiographs at 1, 5, and 15 years post-loading.
Immediate implant placement in molar extraction sockets
This study revealed that implants installed in fresh extraction sockets on molar sites yielded survival rates of 96.6% over a minimum 1 year ...
Preservation and augmentation of molar extraction sites ...
Ridge preservation at periodontally compromised molar extraction sites might compensate for ridge width and buccal bone resorption that occurs ...
Osseodensification Efficacy on Molar Septum Expansion in ...
Immediate implant placement help preserve the alveolar ridge dimensions and buccal ridge contour. While osseodensification has shown promise in enhancing ...
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