Cohealyx for Full Thickness Wounds
(Cohealyx I Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests Cohealyx, a collagen matrix, to evaluate its effectiveness in healing full-thickness wounds after surgery. Researchers aim to determine how quickly Cohealyx can completely close these wounds. Individuals scheduled for surgery requiring a skin graft and hospitalized shortly after their injury may be suitable candidates. The study involves only Cohealyx treatment after cleaning the surgical area. As an unphased trial, it offers a unique opportunity to contribute to medical research and potentially benefit from a novel treatment.
Do I have to stop taking my current medications for the trial?
The trial protocol does not specify if you need to stop taking your current medications. However, if you are using medications that might affect your safety or the trial's evaluations, you may not be eligible to participate.
What prior data suggests that Cohealyx is safe for treating full thickness wounds?
Research has shown that Cohealyx, a skin substitute made from collagen, is designed to help heal wounds. This treatment supports tissue joining and promotes the growth of new blood vessels, which can speed up recovery. The FDA has approved Cohealyx for other wound care uses, indicating it meets certain safety standards. Although detailed information on side effects remains unavailable, FDA approval suggests Cohealyx is generally safe. This offers a hopeful outlook for its use in treating deep wounds.12345
Why are researchers excited about this trial?
Cohealyx is unique because it introduces a novel approach to healing full-thickness wounds. Unlike traditional treatments like skin grafts or synthetic dressings that primarily cover or close the wound, Cohealyx is applied post-surgical excision to potentially enhance the body's natural healing processes. Researchers are excited about Cohealyx because it might offer a more efficient healing process, reducing recovery time and improving overall outcomes for patients with deep, severe wounds. This could be a game-changer, especially for those who struggle with slow-healing wounds.
What evidence suggests that Cohealyx might be an effective treatment for full thickness wounds?
Research has shown that Cohealyx Collagen Matrix may help heal deep wounds. Animal studies found that Cohealyx can create strong tissue, which supports skin grafts effectively. The matrix quickly absorbs blood and fluids, accelerating the healing process. This technology aims to help wounds close completely by providing a solid base for new skin growth. Although more information from human trials is needed, these early findings suggest Cohealyx could be a valuable tool for wound care.12678
Are You a Good Fit for This Trial?
This trial is for patients with full thickness wounds needing skin grafts. They must be hospitalized within 3 days of injury, have surgery within 5 days, and commit to the study's procedures for 26 weeks post-grafting without seeking other treatments or joining another trial.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Initial Treatment
Cohealyx is applied to the surgically excised wound bed within 5 days post-injury
Autografting
Once Cohealyx has integrated, the wound bed is prepared and autografted
Follow-up
Participants are monitored for healing, safety, and adverse events post-autografting
What Are the Treatments Tested in This Trial?
Interventions
- Cohealyx
Find a Clinic Near You
Who Is Running the Clinical Trial?
Avita Medical
Lead Sponsor