Mobile Health Application for HIV Prevention and Drug Addiction

(PA-Links Trial)

SB
EF
Overseen ByEmily F Dauria, PhD
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: Temple University
Must be taking: PrEP, MOUD
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new mobile app designed to help women recently released from jail or prison reduce their HIV risk and manage drug addiction. The app supports medication use for HIV prevention and opioid use disorder management, offering personalized resources, quizzes, and messages to keep users on track. Women who have been in the carceral system within the last six months and are at risk for HIV or opioid use may be suitable for this trial, especially if they have internet access and speak English. As an unphased trial, this study provides a unique opportunity to access innovative support tools and contribute to research that could benefit others in similar situations.

What prior data suggests that this mobile health application is safe for women involved in the carceral system?

Research has shown that mobile health (mHealth) apps are generally safe and well-liked by people living with HIV. These apps assist users in following their treatment plans. For example, one study found that using an app to manage HIV care improved medication adherence. This indicates that the apps are both effective and safe.

Another study examined a mobile health app designed to help people adhere to Pre-Exposure Prophylaxis (PrEP), a medication that prevents HIV. Developers created the app with input from potential users, enhancing its safety and usability.

Regarding safety, mHealth apps have shown very few negative side effects or reactions. They are designed for ease of use, and many people feel comfortable sharing personal information through them. Overall, evidence suggests that these apps provide a safe way to support HIV prevention and treatment.12345

Why are researchers excited about this trial?

Researchers are excited about the Mobile Health Application for HIV Prevention and Drug Addiction because it offers a unique approach to enhancing patient care. Unlike traditional methods that rely solely on in-person navigation services, this app supplements standard care with personalized digital support. It delivers weekly resources tailored to individual needs, interactive quizzes for engagement, and timely reminders about healthcare appointments and medication use. Additionally, it fosters community interaction through an embedded communication feature, providing users with both practical and emotional support. This holistic digital approach aims to improve healthcare access and retention, making it a promising tool in the fight against HIV and drug addiction.

What evidence suggests that this mobile health application is effective for HIV prevention and drug addiction?

Research has shown that mobile health apps can improve health outcomes. For instance, one app increased HIV testing rates from 35.1% to 88.5% in six months. These apps also help users take their medications more regularly. Another study found that they assist individuals in adhering to their HIV care plans and maintaining viral control. For those dealing with substance use, mobile apps have shown promise in supporting individuals who want to quit. In this trial, participants in the intervention arm will access the PA Links web-based app, which aims to enhance usual care by providing resources, quizzes, supportive messages, and reminders. Overall, mobile health apps are proving to be effective tools for better health management.23678

Are You a Good Fit for This Trial?

Inclusion Criteria

Previous experience (past six months) with the carceral system (jail, prison, on parole or under supervision)
Speaks and reads English
Have access to the internet through some device - smart phone, computer or tablet (personal or at community location such as library or organization)
See 5 more

Exclusion Criteria

I do not read or speak English.
I do not identify as a woman.
I have been diagnosed with HIV.
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants engage with the PA-Links web-based app and receive navigation services to increase PrEP and MOUD uptake

3 months
Weekly interactions via app and navigator support

Follow-up

Participants are monitored for linkage to PrEP and MOUD services and assessed for feasibility and acceptability of the intervention

3 months
Follow-up assessments at 3 months post-intervention

What Are the Treatments Tested in This Trial?

Interventions

  • Tool to provide re-entry support and improve linkage to healthcare and social services

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Active Control

Group I: Intervention ArmExperimental Treatment1 Intervention
Group II: Control ArmActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Temple University

Lead Sponsor

Trials
321
Recruited
89,100+

National Institute on Drug Abuse (NIDA)

Collaborator

Trials
2,658
Recruited
3,409,000+

University of Pittsburgh

Collaborator

Trials
1,820
Recruited
16,360,000+

Citations

Efficacy of the mLab App: a randomized clinical trial for ... - PMC

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Efficacy of a Mobile Phone–Based Intervention on Health ...

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Study Details | NCT04855773 | Comparing Mobile Health ...

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Using the Positive Peers Mobile App to Improve Clinical ...

The Positive Peers App (PPA) is a multifunctional HIV support tool designed to improve HIV-related clinical outcomes for young people with HIV.

Development of a Mobile Health Application for HIV ... - PMC

This paper presents results from a participatory design approach in developing the Jichunge mobile app to improve adherence to PrEP among MSM and FSW in ...

Acceptability of an mHealth App That Provides Harm ...

Objective: This study aims to assess the prevalence of smartphone ownership, the level of comfort in providing the personal information required ...

Mobile Health Application - an overview

Mobile Health, or mHealth, describes the use of mobile and wireless communication technologies to improve healthcare delivery, outcomes, and research.