Flicker Stimulation for Memory Loss
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal is to determine whether three months of at least three times / week of sensory flicker stimulation improves cognition, mobility, and affect in older adults with Subjective Cognitive Decline (SCD), relative to an SCD control group receiving white noise sensory stimulation. Investigators will also determine whether the intervention slows cortical thinning and declines in brain functional network segregation and changes in blood biomarkers of Alzheimer's Disease (AD).
Who Is on the Research Team?
Rachael Seidler
Principal Investigator
University of Florida
Are You a Good Fit for This Trial?
This trial is for English-speaking adults aged 65-89 who can walk unassisted, have no dementia or mild cognitive impairment, and experience subjective memory complaints. They must perform daily activities normally but have a family history of dementia. An informant to provide additional information about the participant's cognition is also required.Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive sensory flicker stimulation or white noise sensory stimulation three times a week for three months
Follow-up
Participants are monitored for changes in cognition, mobility, affect, brain structure, and blood biomarkers of Alzheimer's Disease
What Are the Treatments Tested in This Trial?
Interventions
- Flicker Stimulation
- Sham White Noise Stimulation
Trial Overview
The study tests if sensory flicker stimulation three times a week for three months can improve thinking skills, movement, and mood in older adults with Subjective Cognitive Decline (SCD), compared to those receiving sham white noise stimulation. It also examines brain changes and blood markers related to Alzheimer's Disease.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
Participants in this group will receive sensory visual plus auditory flicker stimulation.
Participants in this group will receive white noise sensory stimulation rather than a constant flicker frequency.
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Florida
Lead Sponsor
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