40 Participants Needed

Cognitive Behavioral Therapy for PTSD

Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

A substantial proportion of public safety personnel (PSP) develop service-related posttraumatic stress disorder (PTSD). PTSD is associated with a range of negative outcomes and its exact underlying neurophysiological mechanism is still not well understood. Cognitive behavioral therapy (CBT) is commonly prescribed to treat PTSD, and recent studies suggest that it may be effective in preventing the condition. We have developed a 5-session class focused on teaching introductory CBT skills to prevent and manage psychological distress, and we are currently in the process of launching a clinical trial to demonstrate its effectiveness in preventing PTSD and related conditions in PSP. In the proposed adjunctive study to this trial, we will quantitate the brain connectivity signature that is specific to the PTSD-resilience, and examine whether the classes increase this resilience-related brain mechanism.

Eligibility Criteria

This trial is for public safety personnel who are part of an ongoing study on using Cognitive Behavioral Therapy with Mindfulness (CBTm) to build workplace resilience. It's designed to help prevent PTSD and manage stress.

Inclusion Criteria

Must be enrolled in our on-going parallel study - "Cognitive Behaviour Therapy with Mindfulness Course for Building Workplace Resilience: A Pilot Randomized Controlled Trial

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive 5-week CBTm classes to increase resilience to PTSD

5 weeks
5 sessions (in-person)

Follow-up

Participants are monitored for resilience and PTSD symptoms using fMRI and scales

1 month

Treatment Details

Interventions

  • Cognitive Behavioral Therapy with Mindfulness Class
Trial Overview The trial tests if a 5-session CBTm class can increase brain connectivity associated with resilience against PTSD in public safety workers, by comparing fMRI scans before and after the course.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: ActiveExperimental Treatment1 Intervention
5-week CBTm
Group II: WaitlistedActive Control1 Intervention
Waitlisted (will receive 5-week CBTm 3 months after).

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Manitoba

Lead Sponsor

Trials
628
Recruited
209,000+

University of Regina

Collaborator

Trials
59
Recruited
9,100+
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