Pancreatic Cancer Detection Consortium
(PCDC Trial)
Recruiting at 10 trial locations
AG
Overseen ByAjay Goel, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: City of Hope Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)
Trial Summary
What is the purpose of this trial?
This study aims to prospective validate an exosome-based miRNA signature for noninvasive and early detection of pancreatic ductal adenocarcinoma.
Research Team
AG
Ajay Goel, PhD
Principal Investigator
City of Hope Medical Center
Eligibility Criteria
Inclusion Criteria
My diagnosis is pancreatic cancer at any stage.
I've had all the recommended tests for my cancer and gave a sample before starting treatment.
My tests show no signs of pancreatic cancer.
Timeline
Screening
Participants are screened for eligibility to participate in the trial
2-4 weeks
Training
Participants' miRNA signatures are analyzed to train the detection model
6 months
Validation
The trained model is validated on a separate cohort to confirm its effectiveness
6 months
Follow-up
Participants are monitored for safety and effectiveness after the study
4 weeks
Treatment Details
Participant Groups
4Treatment groups
Experimental Treatment
Group I: Patients with Pancreatic Cancer Ductal Adenocarcinoma (Validation)Experimental Treatment1 Intervention
Individuals diagnosed with pancreatic ductal adenocarcinoma
Group II: Patients with Pancreatic Cancer Ductal Adenocarcinoma (Training)Experimental Treatment1 Intervention
Individuals diagnosed with pancreatic ductal adenocarcinoma
Group III: Individuals without Pancreatic Cancer Ductal Adenocarcinoma (Validation)Experimental Treatment1 Intervention
Individuals without pancreatic ductal adenocarcinoma
Group IV: Individuals without Pancreatic Cancer Ductal Adenocarcinoma (Training)Experimental Treatment1 Intervention
Individuals without pancreatic ductal adenocarcinoma
Find a Clinic Near You
Who Is Running the Clinical Trial?
City of Hope Medical Center
Lead Sponsor
Trials
614
Recruited
1,924,000+
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