2000 Participants Needed

Pancreatic Cancer Detection Consortium

(PCDC Trial)

Recruiting at 10 trial locations
AG
Overseen ByAjay Goel, PhD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: City of Hope Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

This study aims to prospective validate an exosome-based miRNA signature for noninvasive and early detection of pancreatic ductal adenocarcinoma.

Research Team

AG

Ajay Goel, PhD

Principal Investigator

City of Hope Medical Center

Eligibility Criteria

Inclusion Criteria

My diagnosis is pancreatic cancer at any stage.
I've had all the recommended tests for my cancer and gave a sample before starting treatment.
My tests show no signs of pancreatic cancer.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Training

Participants' miRNA signatures are analyzed to train the detection model

6 months

Validation

The trained model is validated on a separate cohort to confirm its effectiveness

6 months

Follow-up

Participants are monitored for safety and effectiveness after the study

4 weeks

Treatment Details

Participant Groups
4Treatment groups
Experimental Treatment
Group I: Patients with Pancreatic Cancer Ductal Adenocarcinoma (Validation)Experimental Treatment1 Intervention
Individuals diagnosed with pancreatic ductal adenocarcinoma
Group II: Patients with Pancreatic Cancer Ductal Adenocarcinoma (Training)Experimental Treatment1 Intervention
Individuals diagnosed with pancreatic ductal adenocarcinoma
Group III: Individuals without Pancreatic Cancer Ductal Adenocarcinoma (Validation)Experimental Treatment1 Intervention
Individuals without pancreatic ductal adenocarcinoma
Group IV: Individuals without Pancreatic Cancer Ductal Adenocarcinoma (Training)Experimental Treatment1 Intervention
Individuals without pancreatic ductal adenocarcinoma

Find a Clinic Near You

Who Is Running the Clinical Trial?

City of Hope Medical Center

Lead Sponsor

Trials
614
Recruited
1,924,000+
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