Your session is about to expire
← Back to Search
Olanzapine for Schizophrenia
Study Summary
This trial will look at whether olanzapine, an atypical antipsychotic medication, affects melatonin levels in patients with schizophrenia, schizoaffective, or bipolar disorder.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
Find a Location
Who is running the clinical trial?
Media Library
- I am not pregnant or breastfeeding.I have taken olanzapine in the last three months.I do not have any major health issues that could worsen by joining this study or affect my participation.You have been diagnosed with substance abuse or addiction in the last 30 days.Patients who the doctor thinks might need to switch to olanzapine will be excluded.I have not taken fluvoxamine, nifedipine, or warfarin in the last 30 days.You have had a serious head injury that caused you to lose consciousness for more than five minutes or have lasting problems with thinking or movement.I have been diagnosed with schizophrenia, schizoaffective disorder, or bipolar disorder.I am not able to have children, am not pregnant, and if sexually active, I use birth control.You have had a bad reaction or couldn't tolerate olanzapine before.I am between 18 and 65 years old.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
- Group 1: IIB (3.0 mg/day melatonin)
- Group 2: IIA (0.3mg day melatonin)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
Frequently Asked Questions
What medical conditions usually respond to treatment with olanzapine and melatonin?
"Olanzapine and melatonin have been clinically demonstrated to ameliorate acute coryza, mental depression, and post traumatic stress disorder (PTSD)."
Is it feasible for me to participate in this experiment?
"The requirements to join this trial are a diagnosis of schizophrenia and an age between 18-65. At present, roughly 20 participants must be recruited."
How many subjects are currently involved with this clinical research?
"The trial, which was initially announced on July 1st 2007 and last modified on October 6th 2022, is no longer seeking participants. For those searching for alternative trials, 2513 studies concerning schizophrenia are currently open to recruitment and 42 medical investigations involving olanzapine in combination with melatonin require patients."
Is the group of participants for this study limited to those under 45 years old?
"This clinical trial is only for those aged between 18 and 65. Patients under 18 have access to 592 trials, while 1597 studies are available to persons over the age of 65."
Are there any existing records of research regarding the combination of olanzapine and melatonin?
"Currently, there are 42 ongoing clinical trials involving olanzapine and melatonin with 8 at the later Phase 3. Of these experiments, a few take place in Toronto but 730 other medical centres across the world have active studies concerning this combination of medications."
Is this an innovatory clinical experiment?
"To date, 42 active clinical trails regarding olanzapine and melatonin have been conducted across 407 cities in 13 nations. The inaugural experiment was commissioned by Eli Lilly & Company in 2007 and featured 20 patients who successfully completed the necessary trials for drug approval. Since then, 335 additional experiments have been carried out."
Is this experiment presently enrolling participants?
"Unfortunately, the trial is not accepting enrolments at present. It was first posted on July 1st 2007 and most recently edited October 6th 2022. Alternatively, there are 2513 trials recruiting people with schizophrenia and 42 studies involving olanzapine and melatonin currently enrolling participants."
Share this study with friends
Copy Link
Messenger