Your session is about to expire
← Back to Search
This trial will look at whether olanzapine, an atypical antipsychotic medication, affects melatonin levels in patients with schizophrenia, schizoaffective, or bipolar disorder.
- Metabolic Syndrome
- Bipolar Disorder
- Schizoaffective Disorder
Inclusion CriteriaYou will be eligible if you check “Yes” for the criteria below
Study ObjectivesOutcome measures can provide a clearer picture of what you can expect from a treatment.
Awards & Highlights
Find a Location
Who is running the clinical trial?
- You have been diagnosed with substance abuse or addiction within the past month.You have had an allergic reaction or experienced severe side effects from taking olanzapine before.You have had a serious head injury that caused you to lose consciousness for more than five minutes or have lasting problems with your brain or thinking abilities.You have taken olanzapine in the last three months.The doctor thinks that switching to olanzapine might help you.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
- Group 1: IIB (3.0 mg/day melatonin)
- Group 2: IIA (0.3mg day melatonin)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
What medical conditions usually respond to treatment with olanzapine and melatonin?
"Olanzapine and melatonin have been clinically demonstrated to ameliorate acute coryza, mental depressiond melatonin have been clinically demonstrated to ameliorate acute coryza, mental depression, and post traumatic stress disorder (PTSD)."
Is it feasible for me to participate in this experiment?
"The requirements to join this trial are a diagnosis of schizophrenia and an age between 18-65. At present, roughly 20 participants must be recruited."
How many subjects are currently involved with this clinical research?
"The trial, which was initially announced on July 1st 2007 and last modified on October 6th 2022, is no longer seeking participants. For those searching for alternative trials, 2513 studies concerning schizophrenia are currently open to recruitment and 42 medical investigations involving olanzapine in combination with melatonin require patients."
Is the group of participants for this study limited to those under 45 years old?
"This clinical trial is only for those aged between 18 and 65. Patients under 18 have access to 592 trials, while 1597 studies are available to persons over the age of 65."
Are there any existing records of research regarding the combination of olanzapine and melatonin?
"Currently, there are 42 ongoing clinical trials involving olanzapine and melatonin with 8 at the later Phase 3. Of these experiments, a few take place in Toronto but 730 other medical centres across the world have active studies concerning this combination of medications."
Is this an innovatory clinical experiment?
"To date, 42 active clinical trails regarding olanzapine and melatonin have been conducted across 407 cities in 13 nations. The inaugural experiment was commissioned by Eli Lilly & Company in 2007 and featured 20 patients who successfully completed the necessary trials for drug approval. Since then, 335 additional experiments have been carried out."
Is this experiment presently enrolling participants?
"Unfortunately, the trial is not accepting enrolments at present. It was first posted on July 1st 2007 and most recently edited October 6th 2022. Alternatively, there are 2513 trials recruiting people with schizophrenia and 42 studies involving olanzapine and melatonin currently enrolling participants."
Share this study with friends