Quality-of-Life Assessment for Oral Squamous Cell Carcinoma

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Roswell Park Cancer Institute, Buffalo, NY
Oral Squamous Cell Carcinoma+1 More
Quality-of-Life Assessment - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This clinical trial compares intensive symptom evaluation with supportive care to standard symptom management in patients with head and neck cancer that has not spread to other places in the body (non-metastatic). Standard symptom management involves symptom management during and after radiation therapy, using problem-focused history and physical examination followed by appropriate symptomatic management as appropriate per treating physician's discretion. Intensive symptom management with monitoring patient reported outcomes is performed among patients with metastatic cancers receiving systemic therapies and with various cancers receiving radiation therapy. This trial may help researchers determine the impact of intensive symptom surveillance in patients with non-metastatic head and neck cancers.

Eligible Conditions

  • Oral Squamous Cell Carcinoma
  • Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Oral Squamous Cell Carcinoma

Study Objectives

1 Primary · 8 Secondary · Reporting Duration: At 1 or 6 month

Month 6
Time to first acute care visits
At 3 months
Time to first acute care visit
Baseline to 6 months
Change in Health-related quality of life EORTC QLQ-C30
Change in caregiver burden
Change in financial burden
Month 6
Overall survival
Month 6
Distant failure
Month 6
Locoregional failure
Month 6
Progression free survival

Trial Safety

Safety Progress

1 of 3

Other trials for Oral Squamous Cell Carcinoma

Trial Design

2 Treatment Groups

Group B (standard symptom management)
1 of 2
Group A (quality of life questionnaire)
1 of 2
Active Control
Experimental Treatment

200 Total Participants · 2 Treatment Groups

Primary Treatment: Quality-of-Life Assessment · No Placebo Group · N/A

Group A (quality of life questionnaire)Experimental Group · 2 Interventions: Quality-of-Life Assessment, Questionnaire Administration · Intervention Types: Other, Other
Group B (standard symptom management)
Other
ActiveComparator Group · 1 Intervention: Palliative Therapy · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: at 1 or 6 month
Closest Location: Roswell Park Cancer Institute · Buffalo, NY
Photo of roswell park cancer institute  1Photo of roswell park cancer institute  2Photo of roswell park cancer institute  3
2011First Recorded Clinical Trial
0 TrialsResearching Oral Squamous Cell Carcinoma
798 CompletedClinical Trials

Eligibility Criteria

Age 18+ · All Participants · 10 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are scheduled to start curative-intent radiation therapy within 4 weeks.
You have biopsy-proven, non-metastatic squamous cell carcinoma of head and neck.
You are able to provide informed consent in English.
The eligible patient identifies a caregiver verbally.
You are providing care for patients without payment.
You are able to read and write in English.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.