Treatment for Spinal Cord Injuries

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Virginia Commonwealth University, Richmond, VA
Spinal Cord Injuries+3 More
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This study is evaluating whether playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.

See full description

Eligible Conditions

  • Spinal Cord Injuries
  • Neuropathic Pain

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 6 secondary outcomes in patients with Spinal Cord Injuries. Measurement will happen over the course of Baseline - 6 months.

Baseline - 6 months
Neurological changes
Month 18
Change in Pain Intensity
Change in Pain Interference
Change in Pain Quality
Change in mood
Change in quality of life
Month 18
Post treatment change

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Virtual reality (VR) game 1
1 of 2
Virtual reality (VR) game 2
1 of 2
Active Control

This trial requires 250 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Virtual reality (VR) game 1
Other
Participants will be asked to play a virtual reality game twice a day for 10 days.
Virtual reality (VR) game 2
Other
Participants will be asked to play a virtual reality game twice a day for 10 days.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: at follow up (up to 18 months)
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly at follow up (up to 18 months) for reporting.

Closest Location

Virginia Commonwealth University - Richmond, VA

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
age of 18 - 65
more than one-year post-injury
persistent NP symptoms that are of daily severity of at least 4/10
endorsement of more than 2 items on a 7-item Spinal Cord Injury Pain Instrument, SCIPI

Patient Q&A Section

Have there been other clinical trials involving treatment?

"The majority of this review suggests that treatment has been tested and validated for patients with spinal cord injuries. These trials provide an overview of the current treatment options. However, few clinical trials have shown to be effective for each case of spinal cord injury. If you are a patient with a spinal cord injury looking to join one of these clinical trials, [Power]." - Anonymous Online Contributor

Unverified Answer

Does treatment improve quality of life for those with spinal cord injuries?

"Patients in this randomized trial had a significantly improved QOL. Findings from a recent study need to be corroborated in a different group of patients with a different mix of injury types and severity." - Anonymous Online Contributor

Unverified Answer

What is spinal cord injuries?

"Spinal cord injuries are a severe disability issue. The [spinal cord injury](https://www.withpower.com/clinical-trials/spinal-cord-injury) is the most common reason of death from SCI, while neurological deficits are the main causes of death in SCI survivors. SCI poses great risk to life, personal mobility and quality of life for SCI survivors. SCI survivors require multidisciplinary attention to meet their needs. SCI survivors should be given the right to physical, functional and psychological rehabilitation as soon as possible." - Anonymous Online Contributor

Unverified Answer

What are common treatments for spinal cord injuries?

"In a recent study, findings no single treatment provided complete relief for all individuals tested. A combination of treatments often provided the best resolution of chronic pain. The current recommendations for treatments for this disorder include referral to a physical therapist for therapy, medications, and spinal cord injury evaluation and assessment with imaging like magnetic resonance imaging, computed tomography angiogram, and electrodiagnostic studies. Exercise, education, and rehabilitation is another main aspect of treatment for chronic pain. Treatment aims to integrate patients into their new functional role in life and to develop a treatment program that maximizes the potential for recovery of maximum function. It is important that surgeons use the most effective treatment that has been shown to reduce the incidence of chronic pain. This will maximize function over time." - Anonymous Online Contributor

Unverified Answer

How many people get spinal cord injuries a year in the United States?

"Approximately 42.7 million people who have been involved in a serious accident are living with a [spinal cord injury](https://www.withpower.com/clinical-trials/spinal-cord-injury), making it the leading cause of non-traumatic disability in the United States. Although spinal cord injuries happen most commonly in pedestrians and motorcyclists, the U.S. Department of Health and Human Services estimates the numbers of people with paralysis due to other causes, such as poisoning and fire, to be as great as those due to falls." - Anonymous Online Contributor

Unverified Answer

What causes spinal cord injuries?

"The majority of SCI cases occur as a result of an accident that involves lifting things, running into things or falling down. In children, bicycle accidents are frequent causes. Almost one-third of all SCI cases occur as a result of sports-related injuries. Another common accident causes SCI in children in which an object or ball is thrown by another child, and it will injure the spinal cord of the throwing child. Sports injuries and bicycle accidents are thought to be the most common causes of traumatic spinal cord injuries." - Anonymous Online Contributor

Unverified Answer

Can spinal cord injuries be cured?

"The degree of injury can influence the prognosis for disability and functional recovery. Nevertheless, there is at least partial functional recovery in a number of patients even after complete motor function loss. However, a full recovery cannot be accomplished with any therapeutic intervention." - Anonymous Online Contributor

Unverified Answer

What are the signs of spinal cord injuries?

"Some spinal cord-related signs and symptoms include decreased sensation of the limbs or face, urinary retention, difficulty breathing, bowel/bladder incontinence and loss of bladder control. Muscle atrophy or wasting is common among persons with spinal cord injuries and may become evident only when the person is a young adult. Spinal tract signals are usually lost at the level of the lesion with a loss of motor and pain sensitivity. Paralysis and muscle atrophy are some of the most prevalent complications associated with spinal cord injuries. Most spinal cord injuries are the result of trauma and the most common injuries resulting from spinal cord trauma are fractures and avulsion type injuries, generally due to traffic accidents." - Anonymous Online Contributor

Unverified Answer

Have there been any new discoveries for treating spinal cord injuries?

"In this retrospective review, there were no new findings on treatment of spinal cord injuries. Based on the data there was a change to earlier administration of corticosteroids and earlier initiation of anticoagulative treatment." - Anonymous Online Contributor

Unverified Answer

Does spinal cord injuries run in families?

"SCI is a complex disease. It is not unusual for familial clustering to occur in the general population. Genetic factors do play an important part, but other environmental factors may also be important. For this reason, we recommend that, at the time of diagnosis, SCI patients be advised to seek a genetic counselor, who should provide reliable information about risk and possible outcomes, as well as support at the time of diagnosis." - Anonymous Online Contributor

Unverified Answer

Is treatment safe for people?

"Treatment is potentially dangerous and can lead to injury. It is particularly unsafe for children, the elderly and the most vulnerable subgroups such as pregnant women. It is important to assess risk. Patient-directed communication about treatment risks is important. [The Royal College of Physicians' "Textbook of General Internal Medicine" advises about this topic but does not state who must get informed of risks and what they should be told. The Royal College of Physicians' "Dictionary of Medical Eponyms" advises that “In medical parlance, risk is the exposure to the possibility that something may happen or the severity of the event that would occur if it were to happen." - Anonymous Online Contributor

Unverified Answer

What is the average age someone gets spinal cord injuries?

"The Centers for Disease Control and Prevention reported that in 2011, the average age when someone got their first spinal cord injury was 39.1 years. Of the 1,852 boys and 4,918 girls born in 2012 and 2013, 40% had no detectable abnormalities on health records of the baby girls; 55% had no detectable abnormalities on health records of the baby boys." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
See if you qualify for this trial
Get access to this novel treatment for Spinal Cord Injuries by sharing your contact details with the study coordinator.