Intermittent Hypoxia (AIH) for Spinal Cord Injuries

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Spinal Cord Injuries+2 More
AIH - Intermittent Hypoxia - hypoxia air mixture - Other
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial will test the effects of acute intermittent hypoxia on leg muscle strength, reflexes, and walking in people with incomplete cervical spinal cord injury.

Eligible Conditions
  • Spinal Cord Injuries

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 1 Secondary · Reporting Duration: Baseline, immediately following intervention (day 5), and at 1, 2, and 4 weeks

Week 4
Change in overground walking endurance
Change in overground walking speed

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Intermittent Hypoxia (AIH)
1 of 2
Intermittent Room Air (SHAM)
1 of 2
Active Control
Non-Treatment Group

20 Total Participants · 2 Treatment Groups

Primary Treatment: Intermittent Hypoxia (AIH) · Has Placebo Group · N/A

Intermittent Hypoxia (AIH)
Other
ActiveComparator Group · 1 Intervention: AIH - Intermittent Hypoxia - hypoxia air mixture · Intervention Types: Other
Intermittent Room Air (SHAM)
Other
ShamComparator Group · 1 Intervention: SHAM - Intermittent Room Air - room air mixture · Intervention Types: Other

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: baseline, immediately following intervention (day 5), and at 1, 2, and 4 weeks

Who is running the clinical trial?

Foundation Wings For LifeOTHER
13 Previous Clinical Trials
1,184 Total Patients Enrolled
10 Trials studying Spinal Cord Injuries
753 Patients Enrolled for Spinal Cord Injuries
Spaulding Rehabilitation HospitalLead Sponsor
123 Previous Clinical Trials
10,456 Total Patients Enrolled
22 Trials studying Spinal Cord Injuries
937 Patients Enrolled for Spinal Cord Injuries
Randy D Trumbower, PT, PhDPrincipal InvestigatorSpaulding Rehabilitation Hospital
5 Previous Clinical Trials
192 Total Patients Enrolled
5 Trials studying Spinal Cord Injuries
192 Patients Enrolled for Spinal Cord Injuries

Eligibility Criteria

Age 18+ · All Participants · 5 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You have motor function below C2-L5 with non---progressive etiology.
You are able to walk without assistance.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 13th, 2021

Last Reviewed: October 7th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.