← Back to Search

Procedure

Prism Adaptation Therapy + Electrical Stimulation for Stroke Rehabilitation

N/A

Recruiting

Led By Fisayo Aloba, PT, DPT

Research Sponsored by Emory University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Young Adults Able Bodied (YAB) Individuals aged 18-30 years, healthy without any physical disability or neurological disorder

Older Adults Able-Bodied Individuals (OAB) aged 45-90 years, healthy without any physical disability or neurological disorder

Timeline

Screening 3 weeks

Treatment Varies

Follow Up pre-training and immediately after training session

Awards & highlights

Study Summary

This trial studies how prism training and electrical stimulation can improve how the brain processes visual information and help people with walking problems.

Who is the study for?

This trial is for healthy young adults (18-30 years), older adults (45-90 years) without disabilities, and individuals aged 40-90 who've had a right hemisphere stroke over 3 months ago. Stroke survivors must have spatial neglect, be able to walk more than 10m, and have certain arm strength. Exclusions include other neurological disorders, severe medical conditions, pregnancy, uncontrolled hypertension, or skin issues where devices attach.Check my eligibility

What is being tested?

The study tests how prism adaptation therapy (PAT), with or without electrical stimulation (E-stim), affects visuospatial behavior and walking in people after a stroke. It also looks at changes in the motor system's neurophysiology. Participants will receive PAT combined with either real or sham E-stim alongside gait training.See study design

What are the potential side effects?

Possible side effects may include discomfort from the electrical stimulation device or irritation at the site of electrode placement. Prism adaptation therapy is generally considered low-risk but could potentially cause mild disorientation or dizziness initially.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am between 18-30 years old and do not have any physical disabilities or neurological disorders.

Select...

I am between 45-90 years old, healthy, and do not have any physical disabilities or neurological disorders.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ pre-training and immediately after training session

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~pre-training and immediately after training session

This trial's timeline: 3 weeks for screening, Varies for treatment, and pre-training and immediately after training session for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in corticospinal excitability (single pulse TMS)

Change in intracortical excitability [paired pulse transcranial Magnetic Stimulation (TMS)]

Change in visuospatial pointing behavior

Secondary outcome measures

Change in computerized line bisection task

Change in spatial neglect deficits

Change in the Catherine Bergego Scale (CBS)

+1 more

Trial Design

3Treatment groups

Experimental Treatment

Active Control

Group I: Stroke with Spatial Neglect (SN) individualsExperimental Treatment3 Interventions

40-90 years individuals with more than 3 months following right hemisphere stroke.

Group II: Old Able-Bodied individualsActive Control2 Interventions

45-90 years old able-bodied individuals (healthy without any physical disability or neurological disorder).

Group III: Young Able-Bodied individualsActive Control2 Interventions

18-30 years old able-bodied individuals (healthy without any physical disability or neurological disorder).

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Emory UniversityLead Sponsor

1,640 Previous Clinical Trials

2,560,622 Total Patients Enrolled

29 Trials studying Stroke

347,997 Patients Enrolled for Stroke

National Institute of Neurological Disorders and Stroke (NINDS)NIH

1,341 Previous Clinical Trials

649,554 Total Patients Enrolled

171 Trials studying Stroke

83,823 Patients Enrolled for Stroke

Fisayo Aloba, PT, DPTPrincipal InvestigatorEmory University

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is the participant requirement for this study age-inclusive?

"Participants must be of legal age and younger than 90 years old to meet the trial's criteria for enrollment."

Answered by AI

What characterizes an ideal candidate for this experiment?

"The prerequisites for taking part in this clinical study are to have had a stroke, and be between 18 years old and 90. This research programme is seeking 35 participants."

Answered by AI

How many individuals have enrolled in this clinical experiment?

"Affirmative. According to the information located on clinicaltrials.gov, this trial is presently recruiting participants; it was initially posted in April 11th 2023 and last updated in September 22nd of that same year. The research requires 35 volunteers from 3 distinct locations."

Answered by AI

Is enrollment open in this research initiative?

"Affirmative. According to the information on clinicaltrials.gov, this analysis is still gathering participants. This research was first published on April 11th 2023 and most recently modified on September 22nd of the same year. The trial requires 35 volunteers at 3 separate sites."

Answered by AI

What is the main goal of this experiment?

"The primary aim of this clinical trial - to be evaluated over a pre-training and immediately post-training session timeline - is to assess the change in intracortical excitability through paired pulse transcranial magnetic stimulation (TMS). Secondary objectives include an analysis of shift in computerized line bisection task performance, Catherine Bergego Scale scores, and weight bearing asymmetry. In particular, stroke patients will have their vertical ground reaction forces measured on a dual belt instrumented treadmill during 3D motion capture for interlimb force comparisons while standing or walking."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Spatial-Motor Stroke-Rehab Study

Trisha Kesar 2023. "Spatial-Motor Stroke-Rehab Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06053320.