Smoking Cessation Programs for Quitting Smoking

Overseen By Dana Carroll, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Masonic Cancer Center, University of Minnesota

Compensation: Varies

Number of Visits: Unknown

Duration: 6 months

416 Participants Needed

Trial Summary

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the treatment Cultural Smoking Cessation Program for quitting smoking?

Research shows that smoking cessation programs, especially those that use technology and are combined with medication, can be effective in helping people quit smoking. These programs can reach many people at a low cost and are often used alongside advice from doctors. ^{1 2 3 4 5}

Is the Cultural Smoking Cessation Program safe for humans?

The available research does not provide specific safety data for the Cultural Smoking Cessation Program, but it suggests that culturally tailored smoking cessation programs have been developed and tested without reported safety concerns. ^{6 7 8 9 10}

What makes the Cultural Smoking Cessation Program unique compared to other smoking cessation treatments?

The Cultural Smoking Cessation Program is unique because it is tailored to the specific cultural values and beliefs of the participants, which can enhance its effectiveness for certain groups, such as Latinos, by making the program more relatable and supportive. ^{10 11 12 13 14}

What is the purpose of this trial?

The aim of this clinical trial is to test the efficacy of a culturally aligned digital smoking cessation resource for American Indian persons who smoke, via a remotely conducted randomized controlled trial.

Eligibility Criteria

This trial is for American Indian adults who smoke at least 3 cigarettes daily, are considering quitting, and have access to a smartphone or tablet. They must be over 18 years old and able to read and speak English.

Inclusion Criteria

I identify as American Indian based on my own understanding.

I have smoked at least 3 cigarettes daily in the last month.

I use a smartphone or tablet daily that can send messages.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive a culturally aligned digital smoking cessation resource via a remotely conducted randomized controlled trial

6 months

Remote interactions

Follow-up

Participants are monitored for smoking cessation outcomes, including quit attempts and abstinence, at 1, 3, and 6 months

6 months

Treatment Details

Interventions

• Cultural Smoking Cessation Program

Trial Overview The study tests a digital smoking cessation program tailored for American Indians against a standard program. Participants will be randomly assigned to one of the two programs in this remote-controlled trial.

Participant Groups

Group I: Tailored Active Control 1 Intervention

Tailored texting program for quit smoking

Group II: Standard Placebo Group 1 Intervention

Standard texting program for quit smoking

Who Is Running the Clinical Trial?

Masonic Cancer Center, University of Minnesota

Lead Sponsor

Trials

285

Recruited

15,700+

University of Minnesota

Collaborator

Trials

1,459

Recruited

1,623,000+

Findings from Research

Computer-based smoking cessation programs are effective and can be delivered on a large scale at a low cost, making them accessible to many smokers.

These programs work best when combined with pharmacotherapy and can serve as a helpful addition to counseling provided by healthcare professionals.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Using new information technology to treat tobacco dependence. Etter, JF.[2017]

A hospital-based smoking cessation program that included behavioral counseling and support was effective, achieving a 32% abstinence rate at 12 months among participants who attended at least two sessions.

Factors such as self-belief in quitting, having a heart condition, and not growing up with smoking siblings were linked to higher chances of long-term abstinence, highlighting the importance of social and psychological influences in quitting smoking.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Effectiveness of hospital-based smoking cessation. Fung, PR., Snape-Jenkinson, SL., Godfrey, MT., et al.[2019]

In a study of 270 heavy nicotine-dependent smokers undergoing a three-week inpatient smoking cessation program, 42.6% were verified as ex-smokers 12 months later, indicating a significant success rate for long-term cessation.

Ex-smokers reported notable improvements in lifestyle satisfaction compared to those who continued smoking, suggesting that the program not only aids in quitting but also enhances overall well-being.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Heavy dependent nicotine smokers--Newfound lifestyle appreciation after quitting successfully. Experiences from inpatient smoking cessation therapy. Schoberberger, R., Böhm, G., Schroeder, Y.[2018]

Smoking cessation counseling provided by physicians and trained health professionals can lead to abstinence rates between 2.1% and 17.4%, indicating some effectiveness in helping people quit smoking.

However, the overall clinical effect of smoking cessation counseling is considered low, and long-term cessation rates remain uncertain, suggesting a need for further cost-effectiveness analyses before widespread implementation in public health programs.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

[Counseling interventions for smoking cessation: systematic review]. Alba, LH., Murillo, R., Castillo, JS.[2019]

The All Nations Snuff Out Smokeless (ANSOS) program was developed specifically for American Indians, who have the highest rates of smokeless tobacco use in the U.S., and showed a 68.8% retention rate with 33 out of 48 participants completing the program.

Among those who completed the program, 34% reported being abstinent from smokeless tobacco, and when accounting for those lost to follow-up, the overall cessation rate was 22.9%, indicating that the program may be effective and culturally appropriate for this population.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Pilot Testing All Nations Snuff Out Smokeless (ANSOS): A Culturally Tailored Smokeless Tobacco Cessation Program for American Indians. Daley, CM., Lewis, C., Nazir, N., et al.[2022]

The 'All Nations Breath of Life' (ANBL) program is being tested as a culturally-tailored smoking cessation intervention specifically for American Indian smokers, with a total of 448 participants involved in the trial.

This study is significant as it is the first controlled trial to evaluate the effectiveness of a culturally-specific approach to smoking cessation in a population with a high smoking prevalence, aiming to address the urgent health crisis among American Indians and Alaska Natives.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Culturally-tailored smoking cessation for American Indians: study protocol for a randomized controlled trial. Choi, WS., Faseru, B., Beebe, LA., et al.[2021]

Proactive referral by healthcare staff significantly increases enrollment rates in behavioral smoking cessation programs, particularly benefiting low-income smokers, as shown in a systematic review of 34 studies.

E-referral systems are more effective and acceptable for implementing proactive referrals compared to traditional fax systems, suggesting that they could enhance access to smoking cessation resources.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Proactive Referral to Behavioral Smoking Cessation Programs by Healthcare Staff: A Systematic Review. van Westen-Lagerweij, NA., Hipple Walters, BJ., Potyka, F., et al.[2023]

References

1. Chile pubmed.ncbi.nlm.nih.gov

[Factors associated with abstinence in a smoking cessation program]. [2015]

2. Switzerland pubmed.ncbi.nlm.nih.gov

Using new information technology to treat tobacco dependence. [2017]

3. United States pubmed.ncbi.nlm.nih.gov

Effectiveness of hospital-based smoking cessation. [2019]

4. Netherlands pubmed.ncbi.nlm.nih.gov

Heavy dependent nicotine smokers--Newfound lifestyle appreciation after quitting successfully. Experiences from inpatient smoking cessation therapy. [2018]

5. Canada pubmed.ncbi.nlm.nih.gov

Adaptation, Implementation Plan, and Evaluation of an Online Tobacco Cessation Training Program for Health Care Professionals in Three Spanish-Speaking Latin American Countries: Protocol of the Fruitful Study. [2022]

6. United States pubmed.ncbi.nlm.nih.gov

Integrating smoking cessation into worker training among Latino immigrant workers: development of a program. [2007]

7. Mexico pubmed.ncbi.nlm.nih.gov

[Counseling interventions for smoking cessation: systematic review]. [2019]

8. United States pubmed.ncbi.nlm.nih.gov

Pilot Testing All Nations Snuff Out Smokeless (ANSOS): A Culturally Tailored Smokeless Tobacco Cessation Program for American Indians. [2022]

9. England pubmed.ncbi.nlm.nih.gov

Culturally-tailored smoking cessation for American Indians: study protocol for a randomized controlled trial. [2021]

10. England pubmed.ncbi.nlm.nih.gov

Evaluation of a culturally appropriate smoking cessation intervention for Latinos. [2022]

11. Denmark pubmed.ncbi.nlm.nih.gov

[Group therapy and smoking cessation]. [2007]

12. Japan pubmed.ncbi.nlm.nih.gov

[Prevention of lung cancer through smoking control activities in Japan]. [2006]

13. Canada pubmed.ncbi.nlm.nih.gov

Efficacy of the Ascure Smoking Cessation Program: Retrospective Study. [2021]

14. England pubmed.ncbi.nlm.nih.gov

Proactive Referral to Behavioral Smoking Cessation Programs by Healthcare Staff: A Systematic Review. [2023]