Skin Properties for Small Fiber Neuropathy Detection
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to find an easier way to detect small fiber neuropathy, a condition causing burning pain and symptoms like dizziness and fatigue. Researchers will analyze skin pictures to identify nerve damage, avoiding the need for complex tests or skin biopsies. This approach could make diagnosis more accessible for those struggling with these symptoms. Individuals who have already undergone specific nerve tests and skin biopsies might be suitable candidates for this study. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could simplify diagnosis for many patients.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications.
Why are researchers excited about this trial?
Researchers are excited about this trial because it explores a novel way to detect small fiber neuropathy through skin properties. Unlike traditional methods that often involve nerve conduction studies or skin biopsies, this approach aims to identify neuropathy by analyzing the skin's characteristics, potentially offering a non-invasive and quicker diagnostic option. This could lead to earlier detection and intervention, improving patient outcomes and quality of life.
What evidence suggests that this method is effective for detecting small fiber neuropathy?
Research has shown that using skin features to detect small fiber neuropathy can be effective. Studies confirmed this method's accuracy by comparing it to skin biopsies, which are commonly used to diagnose the condition. Skin biopsies play a crucial role in identifying small fiber neuropathy, a condition affecting nerves and causing pain and other symptoms. This new method could simplify and broaden access to diagnosis, as it requires no special equipment. It employs mathematical analysis of skin images to identify signs of nerve damage. Early results suggest it could enhance diagnosis availability and help more people receive appropriate treatment.12345
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Image Processing and Diagnosis
Participants undergo specialized image processing of skin pictures to extract statistical features related to loss of small fibers
Verification with Skin Biopsy
The accuracy of the diagnosis is verified using skin biopsies
Follow-up
Participants are monitored for safety and effectiveness after diagnosis
What Are the Treatments Tested in This Trial?
Interventions
- Detection of Small Fiber Neuropathy Using Skin Properties
Find a Clinic Near You
Who Is Running the Clinical Trial?
Brigham and Women's Hospital
Lead Sponsor
Citations
Detection of Small Fiber Neuropathy Using Skin Properties
The accuracy of the diagnosis verified using skin biopsies. This approach can improve the availability of diagnosis of small fiber neuropathy.
A Systematic Review of the Diagnostic Methods of Small Fiber ...
This systematic review describes the several methods to diagnose and measure the severity of small fiber neuropathies and aims to guide the physician.
Small Fiber Neuropathy: A Clinical and Practical Approach
Small fiber neuropathy (SFN) is a peripheral nerve condition causing neuropathic pain and autonomic complaints. Skin biopsy is an important diagnostic tool ...
Validity of Clinical Small-Fiber Sensory Testing to Detect ...
Pinprick testing, followed by warm and cold tests if pinprick is normal, is a valid and cost-effective method to detect small-fiber degeneration.
Which Method for Diagnosing Small Fiber Neuropathy?
This study compares six methods evaluating small sensory and autonomic nerve fibers: skin biopsy, Quantitative Sensory Testing (QST), quantitative sweat ...
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