Angiogenesis Study for Skin Conditions
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to explore how abnormal blood vessel growth (angiogenesis) affects skin conditions such as port wine stains, hemangiomas, rosacea, and psoriasis. Researchers will analyze skin samples to identify patterns and potential treatment targets for these diseases. Participants must be at least 16 years old and willing to undergo a skin biopsy, which involves removing a small skin sample for testing. Individuals with a clinically diagnosed skin condition may find this study suitable. As a Phase 2 trial, the research measures the treatment's effectiveness in an initial, smaller group, offering participants a chance to contribute to important advancements in skin condition treatments.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to ask the trial coordinators for more details.
Why are researchers excited about this trial?
Researchers are excited about this trial because it explores the role of angiogenesis—a process where new blood vessels form—in dermatologic diseases. Unlike standard treatments that primarily address symptoms or inflammation, this approach could uncover new therapeutic targets by examining how blood vessel growth affects skin conditions. By analyzing skin biopsy samples, scientists aim to understand the underlying mechanisms, potentially leading to innovative treatments that address the root cause of these diseases rather than just managing their symptoms.
Who Is on the Research Team?
Kristen Kelly, MD
Principal Investigator
University of California, Irvine
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Sample Collection and Analysis
Biospecimens from dermatologic diseases are collected and analyzed for angiogenic markers. Genetic analysis may be performed on select specimens.
Follow-up
Participants are monitored for safety and effectiveness after sample collection and analysis
What Are the Treatments Tested in This Trial?
Interventions
- Skin Biopsy
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
skin tissue sample
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of California, Irvine
Lead Sponsor
Beckman Laser Institute University of California Irvine
Collaborator
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