1000 Participants Needed

Biologic Specimen Collection for Sickle Cell Trait

Recruiting at 10 trial locations
JK
Overseen ByJulie Kanter, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: National Alliance for Sickle Cell Centers
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to learn more about individuals with Sickle Cell Trait (SCT), a condition where a person carries one sickle cell gene but typically does not exhibit symptoms like those of Sickle Cell Disease. Researchers seek to understand how SCT affects blood and whether it might lead to any health issues over time. The trial seeks adults who know or suspect they have SCT and are willing to confirm their status through testing. Participants will help build a clearer picture of what living with SCT means for their health.

As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research and enhance understanding of SCT's long-term health impacts.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the study team or your doctor.

Why are researchers excited about this trial?

Researchers are excited about the AUNT trial because it aims to deepen our understanding of sickle cell trait, which isn't typically the focus of current treatments. Unlike sickle cell disease, which has established treatment protocols like hydroxyurea and blood transfusions, sickle cell trait often goes unstudied. This trial is unique because it seeks to explore the natural history of the trait, potentially uncovering information that could lead to new insights or interventions. By learning more about how sickle cell trait affects individuals over time, researchers hope to improve health outcomes and provide better guidance for those with the trait.

Who Is on the Research Team?

JK

Julie Kanter, MD

Principal Investigator

National Alliance for Sickle Cell Centers

Are You a Good Fit for This Trial?

Inclusion Criteria

Adults ages 18-65
You are prepared to voluntarily engage and sign the research agreement.
You are aware that you may have Sickle Cell Trait, and are willing to be tested in order to confirm or learn more about it.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Longitudinal Cohort Study

Participants are observed to understand the hematologic phenotype and assess clinical complications of Sickle Cell Trait

2 years

Follow-up

Participants are monitored for safety and effectiveness after the main observation period

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Biologic Specimen Collection

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Individuals with sickle cell traitExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

National Alliance for Sickle Cell Centers

Lead Sponsor

Trials
1
Recruited
1,000+

Beam Therapeutics Inc.

Industry Sponsor

Trials
5
Recruited
1,200+