RemoteEx+ for Inactive Adults

(RemoteEx+ Trial)

Recruiting at 1 trial location

Overseen By Erin Blocker, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Creighton University

Disqualifiers: Cognitive impairment, Neurodegenerative diagnoses, Orthopedic surgery, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 16 weeks

54 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new exercise app, RemoteEx+ Programming, designed to help people in rural areas reduce their risk of Alzheimer's and related dementias. The researchers aim to determine if the app can boost exercise habits, improve quality of life, and lower blood pressure—factors linked to dementia risk. The trial seeks underactive adults who live in rural areas, speak English, and have a smartphone. Participants should be willing to try the app and have approval from their primary care doctor to take part. As an unphased trial, this study offers a unique opportunity to contribute to innovative research that could enhance health outcomes in rural communities.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

What prior data suggests that the RemoteEx+ program is safe for participants?

Research shows that remote exercise programs like RemoteEx+ are generally safe and easy to follow. In a previous study, older women participated in a similar remote exercise program. The study found that the program did not harm the participants. Additionally, participants adhered to the program as planned.

These findings suggest that RemoteEx+ is likely safe for those who try it. While individual experiences may vary, evidence indicates that similar programs have been used successfully without major issues. ^{1 2 3 4 5}

Why are researchers excited about this trial?

RemoteEx+ Programming is unique because it's an innovative approach to increasing physical activity among inactive adults by using remote technology. Unlike traditional exercise programs that require in-person attendance, RemoteEx+ leverages digital platforms to deliver customized exercise routines directly to participants' homes. This remote delivery not only increases accessibility for those who may have mobility or transportation issues but also allows for personalized tracking and adjustments based on individual progress. Researchers are excited about the potential for RemoteEx+ to make exercise more convenient and engaging, potentially leading to higher adherence rates and improved health outcomes compared to conventional methods.

What evidence suggests that the RemoteEx+ program is effective for reducing dementia risk?

Research has shown that remote exercise programs can help older adults enhance their daily activities, movement, and overall physical activity. One study found that these programs increased physical activity in people who work at desks all day. Another study showed that older adults who joined a remote exercise program maintained their ability to move and stay active over time. These results suggest that the RemoteEx+ Program, which participants in this trial will engage with, could improve exercise habits and overall well-being, important factors in lowering the risk of dementia. The program's focus on motivation and education may make it especially beneficial in rural areas. ^{2 6 7 8 9}

Are You a Good Fit for This Trial?

This trial is for adults living in rural Kansas and Nebraska who are not currently active. Participants should be at risk of cognitive impairment and willing to use a smartphone app designed to improve exercise habits.

Inclusion Criteria

Self-reported proficiency in English

Primary care provider clearance to participate for those who do not pass the PAR-Q+

Live in a rural area (Rural-Urban Commuting Area [RUCA] Codes)

Exclusion Criteria

Contraindications to high-intensity exercise

Cognitive impairment (<19 on the Telephone Montreal Cognitive Assessment [MoCA])

I have a condition like Parkinson's, had a stroke, or a brain injury.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in the RemoteEx+ exercise program delivered through a smartphone application, including video demonstrations, workout regimes, motivational messaging, and weekly ADRD risk reduction education

16 weeks

Remote participation via app

Follow-up

Participants are monitored for exercise adherence, efficacy, enjoyment, quality of life, blood pressure, functional mobility, and knowledge of dementia

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• RemoteEx+ Programming

Trial Overview The study tests the RemoteEx+ program, delivered via an app that guides exercises, provides motivational messages, and educates on reducing dementia risk. It aims to increase exercise adherence, enjoyment, efficacy, and quality of life.

How Is the Trial Designed?

Group I: RemoteEx+ Program Experimental Treatment 1 Intervention

Who Is Running the Clinical Trial?

Creighton University

Lead Sponsor

Trials

128

Recruited

25,800+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10155135/

Impacts of Remote Physical Exercises on Functional Status ... To assess whether remote physical exercise interventions helped maintain function in daily life, level of physical activities, basic mobility and frailty ...

2. sciencedirect.com sciencedirect.com/science/article/pii/S1976131724000069

Effects of a Remote Physical Activity Improvement Program ... This study attempted to develop a remote physical activity improvement program for sedentary office workers and verify its effectiveness.

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12433213/

Revolution or Empty Promise? A 6- and 12-Month Follow- ... This follow-up study included 82 independent, home-dwelling older adults (mean age 73.7 ± 3.4; 77% female) who had previously completed a 12- ...

4. sciencedirect.com sciencedirect.com/science/article/pii/S1279770723007662

Feasibility and Acceptability of Remote Physical Exercise ... This study aimed to assess the feasibility and acceptability of remote physical exercise (PE) to prevent mobility loss among pre-disabled older adults during ...

5. formative.jmir.org formative.jmir.org/2024/1/e52428

Feasibility and Acceptability of a Mobile Health Exercise ... We conducted a 3-arm randomized pilot trial of an 8-week intervention for physically inactive adults (ClinicalTrials.gov NCT05192421) that ...

6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11039073/

Feasibility, safety, and adherence of a remote physical and ... The present study met the pre-established criteria for feasibility, safety, and adherence to the remote exercise protocol among older women.

7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12536549/

Defying distance: exercise providers' perspectives on remote ... Remote supports for physical activity offer a promising solution to overcoming barriers to physical activity for older adults (18–20).

8. cdc.gov cdc.gov/physical-activity/php/reports/adults-50-and-older.html

Report: Adults 50 and Older Need More Physical Activity This 2016 study also showed that physical inactivity is higher among adults 50 and older with 1 or more chronic diseases.

9. link.springer.com link.springer.com/article/10.1007/s11121-023-01519-z

Adapting Evidence-Based Falls Prevention Programs for ... We examined the process of adapting and implementing four EBFPPs for remote delivery, best practices for implementing the programs remotely within the RE-AIM ...