Behavioural Intervention

active F8-coil delivered rTMS for Schizophrenia

University of Maryland, Baltimore, Baltimore, MD
Targeting 3 different conditionsactive F8-coil delivered rTMS +1 moreN/ARecruitingLed by Xiaoming Du, PhDResearch Sponsored by University of Maryland, Baltimore

Study Summary

This trial is testing whether transcranial magnetic stimulation can help people with schizophrenia quit smoking.

Eligible Conditions
  • Schizophrenia
  • Smoking Cessation
  • Nicotine Addiction

Eligibility Criteria

Inclusion Criteria

You will be eligible if you check “Yes” for the criteria below
You have smoked within the past year and have been smoking an average of 5 or more cigarettes per day in the past 4 weeks.


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 month
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 month for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Cigarette per day
Resting-state functional connectivity (rsFC) from functional magnetic resonance imaging (fMRI)
Secondary outcome measures
End-expired carbon monoxide (CO)
Fagerstrom Test for Nicotine Dependence (FTND)

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Study groupExperimental Treatment1 Intervention
Participants in this group will receive active F8-coil delivered rTMS.
Group II: Active control groupActive Control1 Intervention
Participants in this group will receive active H-coil delivered rTMS.

Find a site

Who is running the clinical trial?

University of Maryland, BaltimoreLead Sponsor
653 Previous Clinical Trials
370,853 Total Patients Enrolled
63 Trials studying Schizophrenia
10,078 Patients Enrolled for Schizophrenia
Xiaoming Du, PhDPrincipal Investigator
University of Maryland, Baltimore
1 Previous Clinical Trials
60 Total Patients Enrolled
1 Trials studying Schizophrenia
60 Patients Enrolled for Schizophrenia

Media Library

Circuitry-Guided Smoking Cessation in Schizophrenia (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05276050 — N/A
Schizophrenia Research Study Groups: Study group, Active control group
Schizophrenia Clinical Trial 2023: Circuitry-Guided Smoking Cessation in Schizophrenia Highlights & Side Effects. Trial Name: NCT05276050 — N/A
Circuitry-Guided Smoking Cessation in Schizophrenia (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05276050 — N/A
Schizophrenia Patient Testimony for trial: Trial Name: NCT05276050 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it possible to partake in this experiment?

"This medical trial is recruiting 50 individuals with schizophrenia, aged 18 to 60. Those who apply need to fulfil the following prerequisites: gender-neutrality, capacity for written consent, smoking over a year or more at 5 cigarettes per day in the last 4 weeks, clinically diagnosed schizoprenia-spectrum disorder and an Evaluation to Sign Consent score above 10."

Answered by AI

To what extent can this research be conducted with participants?

"Affirmative. attests that this trial is actively recruiting; the details of which were initially posted on June 1st 2022, and updated most recently on November 15th 2022. The study calls for 50 individuals to be recruited at one medical centre."

Answered by AI

Are participants aged 50 and over accepted for this research endeavor?

"The age requirement to be eligible for this medical trial is between 18 and 60 years old."

Answered by AI

Are participants still being accepted for this research endeavor?

"Indeed, verifies that this medical trial is actively recruiting patients since it was first published on June 1st 2022 and updated most recently in November 15th 2022. The research necessitates the recruitment of 50 individuals from a single site."

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
How old are they?
18 - 65
What site did they apply to?
University of Maryland, Baltimore
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?

Why did patients apply to this trial?

I’ve tried quitting smoking and nothing seems to work.

What questions have other patients asked about this trial?

How much does it pay?

How responsive is this trial?

Average response time
  • < 2 Days
Typically responds via
Phone Call
Most responsive sites:
  1. University of Maryland, Baltimore: < 48 hours
~27 spots leftby Feb 2025