Treatment for Schizophrenia

Massachusetts General Hospital, Charlestown, MA
Schizophrenia+1 More Conditions
18 - 55
All Sexes
What conditions do you have?

Study Summary

This trial will test if loneliness and social isolation are linked to how someone perceives and is motivated by social interactions. The findings could help provide new targets for treatments to improve quality of life for those with serious mental illnesses.

Eligible Conditions
  • Schizophrenia
  • Psychosis

Treatment Effectiveness

Study Objectives

4 Primary · 0 Secondary · Reporting Duration: 6 months

6 months
Characterize within-person, dynamic changes in objective isolation and loneliness
Physical health and cardiometabolic/immunological panel
Psychosocial functioning
Trait level social isolation and loneliness

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

0 Treatment Group

120 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · N/A

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 6 months

Who is running the clinical trial?

Boston UniversityOTHER
432 Previous Clinical Trials
9,891,797 Total Patients Enrolled
1 Trials studying Schizophrenia
461 Patients Enrolled for Schizophrenia
Massachusetts General HospitalLead Sponsor
2,782 Previous Clinical Trials
31,225,081 Total Patients Enrolled
44 Trials studying Schizophrenia
9,084 Patients Enrolled for Schizophrenia
Daphne J Holt, MD, PhDPrincipal InvestigatorMassachusetts General Hospital

Eligibility Criteria

Age 18 - 55 · All Participants · 2 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You must be between 18 and 55 years of age.
You have a history of a mental illness that affects your mood or causes you to lose touch with reality.

Frequently Asked Questions

Is enrollment in this experiment currently available to participants?

"According to the database, this study is actively enrolling participants - it was initially posted on July 13th 2022 and its latest update occurred August 22nd of that year." - Anonymous Online Contributor

Unverified Answer

Is the age restriction for this trial above or below 40 years old?

"To be eligible for this research, the age range is 18-55. Those younger than 18 or older than 65 may have more luck finding a suitable trial - 134 and 362 trials respectively cater to these age groups." - Anonymous Online Contributor

Unverified Answer

Is it feasible to join this clinical investigation?

"This research is looking for 120 participants between 18 and 55 years old, diagnosed with schizophrenia who have experienced a psychotic or affective disorder." - Anonymous Online Contributor

Unverified Answer

What is the overall participant capacity of this experiment?

"Affirmative. According to information posted on, recruitment for this trial is currently active and began on July 13th 2022. The last update was published August 22nd 2022 with a need for 120 participants at 1 site." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.