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Social Interaction Perceptions for Mental Illness

N/A

Recruiting

Led By Daphne J Holt, MD, PhD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Experienced a psychotic disorder or mood disorder

Age between 18-55 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

Study Summary

This trial will test if loneliness and social isolation are linked to how someone perceives and is motivated by social interactions. The findings could help provide new targets for treatments to improve quality of life for those with serious mental illnesses.

Who is the study for?

This trial is for individuals aged 18-55 who have experienced serious mental illnesses like psychosis, schizophrenia, or mood disorders. Participants must speak English fluently and not have had any recent medication changes or acute symptoms. They can't join if they've used substances in the past 6 months, have neurological issues, MRI scan exclusions like metal implants, or severe claustrophobia.Check my eligibility

What is being tested?

The study examines how social isolation and loneliness affect brain behavior related to social perception and motivation in people with serious mental illness. It uses EMA (Ecological Momentary Assessment) to track these experiences in real-time and their impact on daily functioning.See study design

What are the potential side effects?

Since this trial involves assessments rather than medications or invasive procedures, there are no direct side effects from interventions. However, participants may experience discomfort discussing personal feelings of loneliness or isolation.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have had a psychotic or mood disorder.

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I am between 18 and 55 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Characterize within-person, dynamic changes in objective isolation and loneliness

Physical health and cardiometabolic/immunological panel

Psychosocial functioning

+1 more

Trial Design

1Treatment groups

Experimental Treatment

Group I: Ecological Momentary AssessmentExperimental Treatment1 Intervention

EMA collected daily (4x/day) for two weeks

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Boston UniversityOTHER

454 Previous Clinical Trials

9,941,450 Total Patients Enrolled

1 Trials studying Schizophrenia

461 Patients Enrolled for Schizophrenia

Massachusetts General HospitalLead Sponsor

2,933 Previous Clinical Trials

13,198,381 Total Patients Enrolled

44 Trials studying Schizophrenia

6,826 Patients Enrolled for Schizophrenia

Daphne J Holt, MD, PhDPrincipal InvestigatorMassachusetts General Hospital

Media Library

Ecological Momentary Assessment Clinical Trial Eligibility Overview. Trial Name: NCT04940663 — N/A

Schizophrenia Research Study Groups: Ecological Momentary Assessment

Schizophrenia Clinical Trial 2023: Ecological Momentary Assessment Highlights & Side Effects. Trial Name: NCT04940663 — N/A

Ecological Momentary Assessment 2023 Treatment Timeline for Medical Study. Trial Name: NCT04940663 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment in this experiment currently available to participants?

"According to the clinicaltrials.gov database, this study is actively enrolling participants - it was initially posted on July 13th 2022 and its latest update occurred August 22nd of that year."

Answered by AI

Is the age restriction for this trial above or below 40 years old?

"To be eligible for this research, the age range is 18-55. Those younger than 18 or older than 65 may have more luck finding a suitable trial - 134 and 362 trials respectively cater to these age groups."

Answered by AI

Is it feasible to join this clinical investigation?

"This research is looking for 120 participants between 18 and 55 years old, diagnosed with schizophrenia who have experienced a psychotic or affective disorder."

Answered by AI

What is the overall participant capacity of this experiment?

"Affirmative. According to information posted on clinicaltrials.gov, recruitment for this trial is currently active and began on July 13th 2022. The last update was published August 22nd 2022 with a need for 120 participants at 1 site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness

Daphne Holt 2022. "Neurobehavioral Mechanisms of Social Isolation and Loneliness in Serious Mental Illness". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04940663.

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