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TMS for Schizophrenia(MESSI Trial)
MESSI Trial Summary
This trial is examining how well a new treatment - navigated repetitive transcranial magnetic stimulation (nrTMS) - works in people with schizophrenia. They are testing to see if this treatment can improve symptoms and cognitive function.
MESSI Trial Eligibility Criteria
Inclusion CriteriaYou will be eligible if you check “Yes” for the criteria below
MESSI Trial Timeline
Study ObjectivesOutcome measures can provide a clearer picture of what you can expect from a treatment.
MESSI Trial Design
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Who is running the clinical trial?
- You speak English as your primary language.You don't have any problems with your brain or nervous system.You have undergone an MRI scan and the results meet the requirements for the study.You are not currently struggling with addiction to alcohol or drugs.You have been diagnosed with schizophrenia, regardless of how long you've had the illness.You are currently experiencing seizures.You have a disorder affecting your nervous system.You are in good overall physical health.You are in good overall physical health.You do not have any problems with your nervous system.You are not currently struggling with addiction to drugs or alcohol.You have wounds or infections on your scalp.You have been diagnosed with schizophrenia, regardless of how long you have had it.You have been stable and receiving outpatient care for at least 12 weeks, and taking low to moderate doses of antipsychotic medication for at least 4 weeks. You have been taking all other psychiatric medications at stable doses.You have metal implants or electronic devices inside your body.You are afraid of being in small spaces and cannot undergo an MRI.
- Group 1: Medial/Superior Prefrontal TMS
- Group 2: Posterior Parietal TMS
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this experiment accept volunteers who are over 35 years old?
"Eligible enrollees for this medical trial must fall between 18 and 60 years old. For those aged under 18, there are 46 trials open to them while 164 studies are available for seniors above 65."
How many participants are enrolling in this medical research project?
"Affirmative. According to clinicaltrials.gov, this medical experiment was initially made public on November 12th 2020 and has since been updated on April 25th 2022. The trial is looking for 160 subjects at a single site of research."
Is this trial providing subjects with the opportunity to participate?
"Affirmative, clinicaltrials.gov has verified that this research is currently recruiting participants. This experiment was initially posted on November 12th 2020 and the most recent update took place April 25th 2022. The trial requires 160 volunteers from 1 site to participate."
Are there specific qualifications for enrolment in this research project?
"The prerequisites for this clinical trial include being between 18 and 60 years old, having schizophrenia but no other neurological conditions, abstaining from alcohol or substance use disorder, good overall physical health, 12 weeks of outpatient status prior to enrolment, plus a 4 week period with lower doses of antipsychotic medication (less than 1000 mg. chlorpromazine equivalents) and stable dosages for all other psychotropic medications. Altogether 160 participants are sought after for the duration of this study."
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