Colorectal surgery for Colorectal Surgery

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
St. Paul's Hospital, Vancouver, CanadaColorectal Surgery+1 MoreColorectal surgery - Procedure
Eligibility
15 - 80
Female
What conditions do you have?
Select

Study Summary

This trial will test whether it is feasible and safe to do a common cancer-preventing surgery, salpingectomy, during another surgery where the fallopian tubes are accessible. If so, this would be a low-cost way to help prevent a cancer with few symptoms and a high death rate.

Eligible Conditions
  • Colorectal Surgery
  • Salpingectomy

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

4 Primary · 1 Secondary · Reporting Duration: Following study completion; an average of 2 years

Hour 2
The percentage of the participants who consented to OS who had both fallopian tubes removed.
During the surgical intervention, a stopwatch will be started when fallopian removal begins and stopped when it is complete (~20 minutes)
The number of additional minutes in the OR required to attempt or complete opportunistic salpingectomy during colorectal surgery (on average)
Year 2
Cost-effectiveness of OS as measured by the cost per quality adjusted life year
Day 30
Incidence of treatment emergent adverse events as assessed by the Clavien Dindo Clavien-Dindo classification of surgical complications.
Week 4
The percentage of participants who consented to OS

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

Colorectal surgery only
1 of 2
Opportunistic salpingectomy
1 of 2

Active Control

Experimental Treatment

240 Total Participants · 2 Treatment Groups

Primary Treatment: Colorectal surgery · No Placebo Group · N/A

Opportunistic salpingectomyExperimental Group · 2 Interventions: Bilateral salpingectomy, Colorectal surgery · Intervention Types: Procedure, Procedure
Colorectal surgery only
Procedure
ActiveComparator Group · 1 Intervention: Colorectal surgery · Intervention Types: Procedure
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Colorectal surgery
2012
N/A
~750

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: following study completion; an average of 2 years

Who is running the clinical trial?

Canadian Cancer Society (CCS)OTHER
72 Previous Clinical Trials
30,719 Total Patients Enrolled
Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,246 Previous Clinical Trials
24,677,888 Total Patients Enrolled
University of British ColumbiaLead Sponsor
1,336 Previous Clinical Trials
1,552,589 Total Patients Enrolled
Gillian Hanley, PhDPrincipal InvestigatorUniversity of British Columbia
Heather Stuart, MDPrincipal InvestigatorUniversity of British Columbia
Carl Brown, MDPrincipal InvestigatorSt. Paul's Hospital

Eligibility Criteria

Age 15 - 80 · Female Participants · 3 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
Women who have not had their fallopian tubes removed.

Frequently Asked Questions

Are any slots still available for participants in this experiment?

"According to the details published on clinicaltrials.gov, this trial is presently seeking candidates. The initial posting was made June 20th 2022 and it has since been amended as recently as June 28th 2022." - Anonymous Online Contributor

Unverified Answer

Is this experiment permissible for geriatric participants?

"To be eligible for this research, prospective participants must fall between the ages of 15 and 80. Additionally, there are two trials designed specifically to include minors aged 18 or below as well as a further 14 studies focusing on individuals 65 years old or above." - Anonymous Online Contributor

Unverified Answer

How many individuals are engaged in the research being done on this subject?

"Affirmative. The clinical trial's listing on clinicaltrials.gov states that the study, which was initially posted on June 20th 2022, is presently seeking enrollees from 1 location and requires 240 subjects in total." - Anonymous Online Contributor

Unverified Answer

May I take part in this experiment?

"This clinical trial is looking to enrol 240 participants aged 15-80 that are scheduled for a colorectal surgery. Candidates must have intact fallopian tubes, and the procedure must be one of the following: total colectomy, right hemicolectomy, left hemicolectomy, anterior resection, low anterior resection, small bowel resection or appendectomy. Furthermore individuals should already have completed their childbearing journey." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.