Natural History Study for Retinitis Pigmentosa
(PHENOROD2 Trial)
Trial Summary
What is the purpose of this trial?
This is natural history study of rods and cones degenerations in patients with Retinitis Pigmentosa (RP) caused by pathogenic mutations in RHO, PDE6a or PDE6b gene mutations.
Will I have to stop taking my current medications?
The trial protocol does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Mobility Test, Ophthalmic examination, Ophthalmic examinations for retinitis pigmentosa?
How does the treatment in the Natural History Study for Retinitis Pigmentosa differ from other treatments?
The research does not provide specific information about a unique treatment for retinitis pigmentosa, as it primarily discusses the evaluation and progression of the disease. Currently, there is no specific therapy for most forms of retinitis pigmentosa, but optical aids and sunglasses are recommended to help manage symptoms.36789
Research Team
Isabelle Audo, MD, PhD
Principal Investigator
CHNO XV-XX Paris - CIC 1423
Eligibility Criteria
This study is for individuals with Retinitis Pigmentosa, a degenerative eye condition, specifically caused by mutations in the RHO, PDE6A or PDE6B genes. Participants must have a certain level of visual acuity and field diameter, understand the local language well enough to follow instructions, and be part of a health system if they're in France. Pregnant women or those with other retinal issues are excluded.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Observation
Participants undergo regular ophthalmic examinations and mobility testing to monitor disease progression
Follow-up
Participants are monitored for safety and effectiveness after the main observation period
Treatment Details
Interventions
- Mobility Test
- Ophthalmic examination
- Ophthalmic examinations
Find a Clinic Near You
Who Is Running the Clinical Trial?
SparingVision
Lead Sponsor