Imaging Retinal Vasculature in Infant Eyes
What You Need to Know Before You Apply
What is the purpose of this trial?
Retinopathy of prematurity is a leading cause of childhood blindness worldwide. The fovea, a critical location in the retina determining visual acuity and visual function, and the blood vessels around it, are abnormally developed in infants with retinopathy of prematurity. However, how these blood vessels form during development of the human fovea remains unclear. This research will advance our understanding of the fundamental knowledge of how the blood vessels around the fovea form in infants, and how they change in diseased states such as preterm birth or retinopathy of prematurity.
Who Is on the Research Team?
Xi Chen, MD
Principal Investigator
Duke University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
ROP Screening and Imaging
Preterm infants undergo ROP screening and imaging to assess perifoveal vascular development
Follow-up
Participants are monitored for changes in vascular density and network morphology after initial imaging
What Are the Treatments Tested in This Trial?
Interventions
- Handheld Optical Coherence Tomography with OCT Angiography
Find a Clinic Near You
Who Is Running the Clinical Trial?
Duke University
Lead Sponsor
University of Pennsylvania
Collaborator
National Institutes of Health (NIH)
Collaborator