V/Q System for Acute Respiratory Distress Syndrome in COVID-19

N/A

Waitlist Available

Led By Maxwell Weinmann, MD

Research Sponsored by Emory University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Presentation with acute respiratory distress syndrome (ARDS) requiring intubation with mechanical ventilator support. ARDS will be defined by the ratio of the partial pressure of oxygen in the patient's arterial blood (PaO2) to the fraction of oxygen in the inspired air (FiO2) as being < 300.

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, hour 1, hour 2, hour 3, hour 4, 1 hour post-intervention

Awards & highlights

Study Summary

This trial is looking at whether a vest that inflates and deflates around the chest can help improve oxygenation for people with ARDS who have COVID-19 and are on mechanical ventilation.

Who is the study for?

This trial is for patients with severe breathing problems due to ARDS from COVID-19, who are on ventilators. They must have a specific oxygenation measurement (PaO2/FiO2 < 300) and consent from a legal representative. It's not for those with recent chest trauma, high brain pressure, certain esophageal conditions, pre-existing lung issues like pulmonary hypertension or fibrosis, skin wounds affected by the Vest device, severe scoliosis, extreme obesity (BMI >37), pregnant women or if they can't maintain an oxygen saturation above 88%.Check my eligibility

What is being tested?

The study tests a non-invasive V/Q System Vest that manipulates chest pressure to improve oxygen levels in ARDS patients caused by COVID-19. The vest inflates and deflates around the patient's chest to change pressures while monitoring their response during and after a four-hour intervention period.See study design

What are the potential side effects?

Potential side effects may include discomfort due to the pressure changes from the vest application. There could also be risks related to worsening of existing injuries or conditions such as hemoptysis (coughing up blood), increased intracranial pressure or aggravating any present cutaneous wounds.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am on a ventilator due to severe lung issues with specific oxygen levels.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, hour 1, hour 2, hour 3, hour 4, 1 hour post-intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, hour 1, hour 2, hour 3, hour 4, 1 hour post-intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, hour 1, hour 2, hour 3, hour 4, 1 hour post-intervention for reporting.