Group treatment h-APC and EMR for Colorectal Cancer

Centre Hospitalier Universitaire de Montréal (CHUM), Montréal, Canada
Colorectal Cancer+1 More ConditionsHybrid Argon Plasma Coagulation and EMR procedure - Procedure
18 - 89
All Sexes

Study Summary

This trialtested a technique to reduce recurrence of colon adenomas after surgery. It found post-EMR ablation of resection margins using soft coagulation and h-APC reduced recurrence to 5%.

Eligible Conditions
  • Colorectal Cancer
  • Colon Polyps

Treatment Effectiveness

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 14 days after the index EMR

Day 14
Completeness of thermal ablation of polyp resection margin
To evaluate the uniformity of the margins and bases of resection after hAPC ablation following an EMR.
Month 6
Evaluate adenoma recurrence rate
Year 1
Evaluate complete adenoma eradication rates

Trial Safety

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

1 Treatment Group

Group treatment h-APC and EMR
1 of 1

Experimental Treatment

300 Total Participants · 1 Treatment Group

Primary Treatment: Group treatment h-APC and EMR · No Placebo Group · N/A

Group treatment h-APC and EMR
Experimental Group · 1 Intervention: Hybrid Argon Plasma Coagulation and EMR procedure · Intervention Types: Procedure

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 14 days after the index emr

Who is running the clinical trial?

Erbe Elektromedizin GmbHIndustry Sponsor
8 Previous Clinical Trials
222 Total Patients Enrolled
Penn State UniversityOTHER
333 Previous Clinical Trials
120,931 Total Patients Enrolled
University of MilanOTHER
234 Previous Clinical Trials
291,968 Total Patients Enrolled
Dr John levenickUNKNOWN
Dr Alessandro RepiciUNKNOWN
Centre hospitalier de l'Université de Montréal (CHUM)Lead Sponsor
341 Previous Clinical Trials
116,664 Total Patients Enrolled
Daniel von RentelnPrincipal InvestigatorCentre hospitalier de l'Université de Montréal (CHUM)
5 Previous Clinical Trials
1,464 Total Patients Enrolled

Eligibility Criteria

Age 18 - 89 · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
People of all ethnicities and races are eligible to participate.

Frequently Asked Questions

Is enrollment for this study currently open?

"The hunt for participants is ongoing, as indicated by the records on The study was first uploaded to this database on August 26th 2019 and saw its last update occur on November 28th 2022." - Anonymous Online Contributor

Unverified Answer

Is this research trial open to individuals 45 years of age and older?

"The requirements for patient enrollment stipulate that they must be aged 18-89. For younger or elder individuals respectively, there are 192 and 1572 clinical trials available to them." - Anonymous Online Contributor

Unverified Answer

How many participants are allowed to partake in this research endeavor?

"Affirmative. The particulars on demonstrate that this investigation is actively seeking participants, with the first posting of the trial occuring August 26th 2019 and a most recent update taking place November 28th 2022. 300 individuals are needed from 1 medical centre for enrollment in this study." - Anonymous Online Contributor

Unverified Answer

Is there a requirement to qualify for enrolling in this experiment?

"This medical trial is seeking 300 individuals aged 18 to 89 with colorectal carcinoma. Patients must be of any ethnicity or race and have been referred for endoscopic resection of all colorectal polyps non-pedunculated equal or greater 20 mm, in addition to providing written informed consent." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.