Study Summary
This trialtested a technique to reduce recurrence of colon adenomas after surgery. It found post-EMR ablation of resection margins using soft coagulation and h-APC reduced recurrence to 5%.
- Colorectal Cancer
- Colon Polyps
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
2 Primary · 2 Secondary · Reporting Duration: 14 days after the index EMR
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
1 Treatment Group
Group treatment h-APC and EMR
1 of 1
Experimental Treatment
300 Total Participants · 1 Treatment Group
Primary Treatment: Group treatment h-APC and EMR · No Placebo Group · N/A
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18 - 89 · All Participants · 1 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Motchum L, Levenick JM, Djinbachian R, Moyer MT, Bouchard S, Taghiakbari M, Repici A, Deslandres E, von Renteln D. Endoscopic mucosal resection combined with hybrid argon plasma coagulation to prevent recurrence of large nonpedunculated colorectal polyps. Gastrointest Endosc. 2022 Jun 17. pii: S0016-5107(22)01769-2. doi: 10.1016/j.gie.2022.06.018. [Epub ahead of print]
- Motchum L, Levenick JM, Djinbachian R, Moyer MT, Bouchard S, Taghiakbari M, Repici A, Deslandres É, von Renteln D. EMR combined with hybrid argon plasma coagulation to prevent recurrence of large nonpedunculated colorectal polyps (with videos). Gastrointest Endosc. 2022 Jun 18. pii: S0016-5107(22)01769-2. doi: 10.1016/j.gie.2022.06.018. [Epub ahead of print]
- Motchum L, Levenick JM, Djinbachian R, Moyer MT, Bouchard S, Taghiakbari M, Repici A, Deslandres É, von Renteln D. EMR combined with hybrid argon plasma coagulation to prevent recurrence of large nonpedunculated colorectal polyps (with videos). Gastrointest Endosc. 2022 Nov;96(5):840-848.e2. doi: 10.1016/j.gie.2022.06.018. Epub 2022 Jun 18.
- Motchum L, Levenick JM, Djinbachian R, Moyer MT, Bouchard S, Taghiakbari M, Repici A, Deslandres E, von Renteln D. EMR combined with hybrid argon plasma coagulation to prevent recurrence of large nonpedunculated colorectal polyps (with videos). Gastrointest Endosc. 2022 Nov;96(5):840-848.e2. doi: 10.1016/j.gie.2022.06.018. Epub 2022 Jun 18.
- 2019. "Hybrid-APC Margin Ablation to Prevent Post EMR Adenoma Recurrence". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04015765.
Frequently Asked Questions
Is enrollment for this study currently open?
"The hunt for participants is ongoing, as indicated by the records on clinicaltrials.gov. The study was first uploaded to this database on August 26th 2019 and saw its last update occur on November 28th 2022." - Anonymous Online Contributor
Is this research trial open to individuals 45 years of age and older?
"The requirements for patient enrollment stipulate that they must be aged 18-89. For younger or elder individuals respectively, there are 192 and 1572 clinical trials available to them." - Anonymous Online Contributor
How many participants are allowed to partake in this research endeavor?
"Affirmative. The particulars on clinicaltrials.gov demonstrate that this investigation is actively seeking participants, with the first posting of the trial occuring August 26th 2019 and a most recent update taking place November 28th 2022. 300 individuals are needed from 1 medical centre for enrollment in this study." - Anonymous Online Contributor
Is there a requirement to qualify for enrolling in this experiment?
"This medical trial is seeking 300 individuals aged 18 to 89 with colorectal carcinoma. Patients must be of any ethnicity or race and have been referred for endoscopic resection of all colorectal polyps non-pedunculated equal or greater 20 mm, in addition to providing written informed consent." - Anonymous Online Contributor