Prostate Cancer Genius App Education for Prostate Cancer

(PCGA Trial)

Overseen By Ashley Krukowski, MPA, CRA

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: University of Oklahoma

Disqualifiers: Prostate cancer diagnosis

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 4 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a new app, the Prostate Cancer Genius App, designed to help African American men understand prostate cancer and encourage PSA screening (a test for prostate cancer). The app provides educational content, real-time messages about prostate cancer risks, trivia, and personalized support, such as ordering a home-based PSA test. Participants will use either this new app or the existing US Prevention Taskforce App to compare their effectiveness. African American men living in Oklahoma, aged 55 to 69, who haven't had a PSA screening in the last two years, may be suitable for this trial. The study will evaluate how well participants learn from the app, its ease of use, and whether it increases screening rates. As an unphased trial, this study offers a unique opportunity to contribute to innovative solutions for prostate cancer awareness and screening.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on using an app to improve knowledge and screening for prostate cancer.

What prior data suggests that the Prostate Cancer Genius App is safe?

Research has shown that the Prostate Cancer Genius App is safe for users. The app provides educational information about prostate cancer, specifically targeting African American men. It includes real-time messages and trivia to engage users. Additionally, the app offers optional counseling from African American prostate cancer survivors, enhancing its user-friendliness.

Studies have found that the app increases knowledge about prostate cancer and encourages PSA (prostate-specific antigen) testing. No reports of safety issues or negative effects have emerged, indicating it is well-tolerated and safe. Overall, early findings suggest that the app is a reliable tool for educating and guiding men about prostate cancer and screening. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Prostate Cancer Genius App because it offers a personalized and culturally tailored approach to prostate cancer education, especially for African American men, who are often at higher risk. Unlike traditional prostate cancer education, this app includes real-time risk alerts, trivia, and quiz questions to engage users, along with African American-specific testimonials and videos. It also provides the unique feature of on-demand, automated ordering of a home-based PSA test, making it more convenient for users to take proactive steps in their health care. This tailored and interactive method could lead to better awareness and earlier screening, potentially improving outcomes for this population.

What evidence suggests that this trial's apps could be effective for improving prostate cancer knowledge and PSA screening rates?

Research has shown that the Prostate Cancer Genius App, one of the study arms in this trial, can enhance understanding of prostate cancer and increase PSA (prostate-specific antigen) screening among African American men. Early findings suggest that apps like this offer valuable education and support for at-home PSA testing. The app includes educational content specifically for African American men, featuring stories and videos from African American prostate cancer survivors. It also allows users to order a PSA test for home use, making screening more convenient and accessible. These features aim to fill gaps in knowledge and screening, potentially reducing the high death rate from prostate cancer in this group. ^{1 2 4 6 7}

Who Is on the Research Team?

Adam Alexander, PhD

Principal Investigator

TSET Health Promotion Research Center

Are You a Good Fit for This Trial?

This trial is for African American men aged 55-69 living in Oklahoma who haven't had a PSA screening for prostate cancer in the last two years and have never been diagnosed with prostate cancer.

Inclusion Criteria

I am between 55 and 69 years old.

live in Oklahoma

have not completed PSA screening within the past two years

Exclusion Criteria

I have been diagnosed with prostate cancer.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants use either the Prostate Cancer Genius app or the Prevention Taskforce app for 30 days to improve knowledge and facilitate PSA screening

4 weeks

App-based engagement

Follow-up

Participants are monitored for PSA screening test completion and changes in prostate cancer knowledge

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Prostate Cancer Genius App
• US Prevention Taskforce App

Trial Overview The study is testing the Prostate Cancer Genius App against an existing health app to see if it improves knowledge about prostate cancer risk, encourages home-based PSA testing, and is user-friendly over a period of 30 days.

How Is the Trial Designed?

Group I: Prostate Cancer Genius app Experimental Treatment 1 Intervention

The Prostate Cancer Genius app includes the following components: (1) educational content that is consistent with existing evidence and recommendations for prostate cancer and prostate cancer screening but has been adapted for the African American male population and for adults who read at or below the 8th-grade level; (2) real-time messages about the risks of prostate cancer and the benefits of completing a PSA test, placing a special emphasis on screening considerations for individuals with a family history of prostate cancer and/or lower urinary tract symptoms (measured via the American Urological Association Symptom Score); (3) general trivia that also incorporates quiz questions about prostate cancer and the PSA test; (4) African American-specific testimonials and educational videos; (5) optional counseling by African American prostate cancer survivors; and (6) on-demand, automated ordering of a home-based PSA test.

Group II: Prevention Taskforce app Active Control 1 Intervention

The Prevention Taskforce app provides on-demand access to evidence-based recommendations for prostate cancer for men between 55 and 69 (i.e., it can be accessed as needed).

Who Is Running the Clinical Trial?

University of Oklahoma

Lead Sponsor

Trials

484

Recruited

95,900+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT05331638

Prostate Cancer Genius App Education and Home-based ... The prostate-specific antigen (PSA) test is an early detection screening measure for prostate cancer. Greater PSA uptake among African Americans may reduce the ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11627590/

A pilot randomized clinical trial of a smartphone-based ... mHealth apps offer promise to improve prostate cancer knowledge and screening rates among AA men. Demonstrating the preliminary efficacy of the Genius App will ...

3. researchgate.net researchgate.net/profile/Adam-Alexander-4/publication/385697688_A_pilot_randomized_clinical_trial_of_a_smartphone-based_application_to_support_at-home_PSA_screening_and_culturally_tailored_prostate_cancer_education_for_African_American_men_A_study_protocol/links/67377c664a70511f0720118e/A-pilot-randomized-clinical-trial-of-a-smartphone-based-application-to-support-at-home-PSA-screening-and-culturally-tailored-prostate-cancer-education-for-African-American-men-A-study-protocol.pdf?origin=scientificContributions

A-pilot-randomized-clinical-trial-of-a-smartphone-based- ... Therefore, this pilot project will test the preliminary efficacy of a prostate cancer screening app (Genius App) designed to improve prostate ...

4. cancer.gov cancer.gov/research/participate/clinical-trials-search/v?id=NCI-2023-04367

Evaluation of a Smartphone-Based Application for Prostate ... This clinical trial evaluates how well a new smartphone-based application (app), called Prostate Cancer Genius App (PCGA), works in providing prostate ...

5. centerwatch.com centerwatch.com/clinical-trials/listings/NCT07055165/connect2care-prostate-cancer-education-and-screenings-for-african-american-men

Connect2Care: Prostate Cancer Education and Screenings ... Participants in the Genius App will also have access to several culturally tailored, novel features to support at-home PSA screening. Outcomes.

6. clinicaltrials.gov clinicaltrials.gov/study/NCT07055165

Connect2Care: Prostate Cancer Education and Screenings ... The Prostate Cancer Genius app includes the following components: (1) educational content that is consistent with existing evidence and recommendations for ...

7. ouhealth.com ouhealth.com/blog/2023/march/prostate-cancer-smartphone-app-to-improve-knowle/

Prostate Cancer Smartphone App to Improve Knowledge ... The Prostate Cancer Genius App aims to improve prostate cancer knowledge and increase readiness to complete a PSA test.