Telerehabilitation for Prostate Cancer

Overseen By Manish Kohli, MD

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: University of Utah

Must be taking: Androgen deprivation therapy

Disqualifiers: Unstable angina, Hypertension, Myocardial infarction, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores the benefits of a 12-week remote telerehabilitation program for men with high-risk or metastatic prostate cancer undergoing standard hormone therapy (ADT). The trial focuses on improving quality of life and easing access to rehabilitation for patients in rural areas. Physical therapists will create personalized exercise plans for participants. Men with prostate cancer who are currently on ADT and live in rural areas might be a good fit for this trial. As an unphased trial, this study offers a unique opportunity for participants to contribute to innovative research that could enhance rehabilitation access and quality of life for others in similar situations.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It might be best to discuss this with the trial coordinators or your doctor.

What prior data suggests that this telerehabilitation is safe for prostate cancer patients?

Studies have shown that telerehabilitation is safe for cancer patients. Research indicates it is not only safe but also feasible for those recovering from cancer, including patients undergoing treatments like surgery or therapy for prostate cancer. One study found that home-based telerehabilitation is both safe and practical for patients before prostate surgery. Additionally, many other studies have confirmed the safety of this approach for cancer recovery. While every treatment has its own considerations, evidence so far suggests that telerehabilitation is well-tolerated and safe. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about telerehabilitation for prostate cancer because it offers a remote, personalized approach to recovery, unlike traditional in-person physical therapy sessions. This method allows a physical therapist to tailor an individualized rehabilitation plan based on a remote assessment, adapting exercise regimens to fit each participant's specific needs and capabilities. The convenience of participating from home and the ability to customize workouts make it a potentially more flexible and accessible option for patients recovering from prostate cancer treatment.

What evidence suggests that telerehabilitation is effective for prostate cancer?

Research has shown that telerehabilitation, which involves therapy sessions over the phone or internet, can help prostate cancer patients feel better and manage symptoms more effectively. In this trial, participants will engage in a multimodal telerehabilitation program for 12 weeks. Studies have found that these programs aid in recovery and reduce cancer-related symptoms. Telerehabilitation is safe and practical, often improving heart and lung fitness and overall physical activity. Home-based programs have been especially helpful for those undergoing treatments like surgery. Overall, telerehabilitation offers a promising way to support cancer recovery, particularly for people in remote areas. ^{1 3 6 7 8}

Who Is on the Research Team?

Manish Kohli, MD

Principal Investigator

Huntsman Cancer Institute/ University of Utah

Are You a Good Fit for This Trial?

This trial is for individuals with advanced prostate cancer, specifically those receiving androgen deprivation therapy (ADT) for high-risk or metastatic cases. It's aimed at patients living in rural areas who may face challenges accessing rehabilitation services.

Inclusion Criteria

Residing in a rural community, as indicated by zip code in RUCA areas

I am a man being treated with hormone therapy for advanced prostate cancer.

I have been diagnosed with prostate cancer.

Exclusion Criteria

Engaged in a regular exercise rehabilitation program

Relocation plans within next 3 months

Participating in another clinical trial

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants engage in a 12-week multimodal telerehabilitation program, including individualized exercise regimens and interactive education sessions

12 weeks

Remote supervision and interactive sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Telerehabilitation Unit

Trial Overview The study tests a 12-week multimodal telerehabilitation program designed to improve quality of life and manage symptoms related to prostate cancer treatment. The focus is on assessing the usability, acceptability, and adherence to exercise through remote rehabilitation methods.

How Is the Trial Designed?

Group I: Multimodal Telerehabilitation Experimental Treatment 1 Intervention

Participation in a remote telerehabilitation program for 12 weeks. Based on the remote physical therapy assessment, a physical therapist will prescribe an individualized rehabilitation plan to each participant. Exercise regimens, lengths of sessions, repetition counts, and frequency of workouts may be tailored depending on individual needs and capabilities.

Who Is Running the Clinical Trial?

University of Utah

Lead Sponsor

Trials

1,169

Recruited

1,623,000+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07093177

Multimodal Telerehabilitation of Rural Patients With ... Recent studies demonstrated the efficacy of multimodal rehabilitation for functional recovery, improvements in QoL, reduction in cancer symptoms, and secondary ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC8768007/

Telerehabilitation's Safety, Feasibility, and Exercise Uptake ... Conclusions. Telerehabilitation is safe, feasible, and improved outcomes for cancer survivors. Learnings from this study may inform the ongoing ...

3. sciencedirect.com sciencedirect.com/science/article/pii/S1462388925001279

Home based prehabilitation in prostate cancer patients ... This study demonstrates the safety and feasibility of a home-based, telehealth prehabilitation program for patients undergoing radical prostatectomy.

4. bmccancer.biomedcentral.com bmccancer.biomedcentral.com/articles/10.1186/s12885-024-12348-w

Effect of exercise-based cancer rehabilitation via telehealth This meta-analysis showed that telehealth exercise cancer rehabilitation could significantly increase cardiorespiratory fitness and physical activity levels ...

5. clinicaltrials.gov clinicaltrials.gov/study/NCT06981026?cond=Telehealth&aggFilters=status:not%20rec%20ava&viewType=Table&rank=6

The Effectiveness of Telemedicine Monitoring ... The Effectiveness of Telemedicine Monitoring Prehabilitation in Prostate Cancer Patients Undergoing Radical Prostatectomy. ClinicalTrials.gov ID NCT06981026.

6. clinicaltrials.gov clinicaltrials.gov/study/NCT07032584

Impact of Multimodal Telerehabilitation in Rural Patients ... Prostate cancer patients receiving androgen deprivation therapy frequently experience debilitating side effects significantly affecting their quality of life.

7. cancer.jmir.org cancer.jmir.org/2024/1/e56969

Telemedicine Applications for Cancer Rehabilitation: Scoping ... Telerehabilitation for patients with cancer is beneficial and feasible, with diverse approaches in study design, technologies, exercises, and outcomes.

8. link.springer.com link.springer.com/article/10.1007/s00520-024-08803-w

'Making a connection': a qualitative study of experiences ... The safety, feasibility, and efficacy of telerehabilitation for individual cancer rehabilitation is well established [13,14,15,16,17,18].