76 Participants Needed

Attachment & Biobehavioral Therapy + Depression Treatment for Depression & Disruptive Behaviors

(ABC+D Trial)

DR
Overseen ByDanielle Roubinov, PhD
Age: Any Age
Sex: Female
Trial Phase: Academic
Sponsor: University of California, San Francisco
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

Maternal depression influences the development of children's behavior problems and vice versa; however most interventions singularly address maternal depression or children's behavior problems rather than both. This project assesses the efficacy of an intervention that treats both mothers and children in an integrated manner. Effects are expected to disrupt the reciprocal relations that perpetuate maternal and child mental health problems over time.

Research Team

DR

Danielle Roubinov, PhD

Principal Investigator

University of California, San Francisco

Eligibility Criteria

This trial is for mothers over 18 with significant depressive symptoms and their biological children aged 2-4 who show heightened behavior problems. Mothers must score at least 16 on the CESD-R depression scale, and children need a score of 18+ on the ECSA behavior assessment. It's not for those with a child diagnosed with autism or mothers with psychosis or active suicidality.

Inclusion Criteria

I speak English or Spanish.
I am a mother over 18 with depression symptoms scoring 5+ on the PHQ-9.
My child, aged 2-4, has significant behavior issues as per a specific rating scale.

Exclusion Criteria

I have a history of psychosis or have recently planned or attempted suicide.
Child diagnosis of autism

Treatment Details

Interventions

  • Attachment and Biobehavioral Catch up
  • Attachment and Biobehavioral Catch up Plus Depression Treatment
Trial OverviewThe study tests an integrated treatment approach addressing both maternal depression and children's behavioral issues simultaneously. One group receives Attachment and Biobehavioral Catch-up (ABC) plus additional depression therapy, while another just gets ABC to see if combined treatment is more effective.
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: ABC+DExperimental Treatment1 Intervention
Attachment and Biobehavioral Catch-up plus weekly 5-10 minute videos that additional provide support for mothers' mood, stress, and coping
Group II: ABCActive Control1 Intervention
Attachment and Biobehavioral Catch-up, 10 weekly sessions that provide parenting support

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of California, San Francisco

Lead Sponsor

Trials
2,636
Recruited
19,080,000+

National Institute of Mental Health (NIMH)

Collaborator

Trials
3,007
Recruited
2,852,000+