Apple Cider Vinegar for Blood Sugar Control

Overseen By Marc Moulin, PhD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Bragg Live Food Products

Must not be taking: Glucose metabolism drugs

Disqualifiers: Pregnancy, Diabetes, Cardiovascular, others

Compensation: Varies

Number of Visits: 1

Duration: 1 day

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests whether apple cider vinegar (ACV) can help control blood sugar levels after eating. Participants will take a Bragg ACV supplement before meals to determine its effect on managing blood sugar rise compared to a placebo (a pill with no active ingredient). The trial seeks individuals with high blood sugar but not diabetes, along with other health markers such as a larger waist size or high blood pressure. Participants should maintain their normal diet and lifestyle during the study. As an unphased trial, it offers participants the chance to contribute to understanding the potential health benefits of ACV.

Do I need to stop taking my current medications to join the trial?

The trial requires participants to maintain their current lifestyle habits, including medications, as much as possible. However, if you are taking medications that might affect glucose metabolism, you may not be eligible to participate.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that apple cider vinegar (ACV) is generally safe for consumption. Studies have found that daily use of ACV can help manage blood sugar and cholesterol levels without major side effects. Some evidence suggests that ACV might slightly lower blood sugar levels, but it should not replace diabetes medications. Including ACV in a plan to control blood sugar is considered safe.

Studies available report no serious negative effects from ACV. However, it should be used in moderation. For any concerns or specific health conditions, consulting a healthcare provider before starting any new supplement is advisable. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Unlike the standard treatments for blood sugar control, which often include medications like metformin or insulin, the Bragg Apple Cider Vinegar (ACV) Supplement is derived from natural apple cider vinegar. Researchers are excited about this treatment because it contains acetic acid, zinc, and vitamin D, which are thought to work together to help manage blood sugar levels. This combination offers a unique approach that could provide a more holistic and potentially less invasive option for blood sugar management. The natural ingredients and simplicity of the supplement make it an appealing alternative for those seeking lifestyle-based interventions.

What evidence suggests that this treatment might be an effective treatment for blood sugar control?

Research has shown that apple cider vinegar (ACV) can help manage blood sugar levels. Studies have found that ACV may lower fasting blood sugar and A1C, which measures average blood sugar over time. Another study found that ACV reduced total cholesterol and fasting blood sugar, aiding in blood sugar control. Daily ACV intake has been linked to better blood sugar management and improved insulin function. This trial will evaluate the Bragg Apple Cider Vinegar Supplement, which participants may receive, to assess its effectiveness in controlling blood sugar levels after meals. ^{1 2 5 6 7}

Who Is on the Research Team?

David Crowley, MD

Principal Investigator

KGK Science Inc.

Are You a Good Fit for This Trial?

This trial is for healthy adults interested in managing their blood sugar levels. Participants should not have any chronic health conditions that could affect blood glucose or be taking medications that influence insulin sensitivity.

Inclusion Criteria

I am between 20 and 50 years old.

I agree to keep my lifestyle, including diet and exercise, the same during the study.

Provided voluntary, written, informed consent to participate in the study

Exclusion Criteria

Alcohol or drug abuse within the last 12 months

Self-reported confirmation of blood/bleeding disorders as assessed by the QI

Participation in other clinical research studies 30 days prior to baseline as assessed by the QI

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants consume an apple cider vinegar supplement 10 minutes prior to a standardized meal

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

8 days

What Are the Treatments Tested in This Trial?

Interventions

• Bragg Apple Cider Vinegar Supplement
• Placebo

Trial Overview The study tests if taking Bragg Apple Cider Vinegar (ACV) supplements before a meal can control blood sugar better than a placebo. Each participant will take the supplement or placebo before eating a set meal to compare effects on their post-meal blood sugar.

How Is the Trial Designed?

Group I: Bragg ACV Supplement Experimental Treatment 1 Intervention

Bragg Apple Cider Vinegar (ACV) Supplement contains apple cider vinegar (standardized to 750 mg of acetic acid), zinc, and vitamin D.

Group II: Placebo Placebo Group 1 Intervention

Placebo supplement contains microcrystalline cellulose.

Who Is Running the Clinical Trial?

Bragg Live Food Products

Lead Sponsor

KGK Science Inc.

Industry Sponsor

Trials

82

Recruited

6,400+

Najla Guthrie

KGK Science Inc.

Chief Executive Officer since 1997

Research career at the Centre for Human Nutrition, University of Western Ontario

Dr. Bibiane Zakaria

KGK Science Inc.

Chief Medical Officer since 2023

MD from an unspecified institution

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10679383/

The improvement effect of apple cider vinegar as a ... Daily consumption of ACV may have beneficial effects in controlling blood glucose indices and lipid profile in patients with type 2 diabetes.

2. clinicaltrials.gov clinicaltrials.gov/study/NCT07043478

A Clinical Trial to Investigate the Efficacy of Bragg Apple ... The goal of this clinical study is to investigate the efficacy of a Bragg Apple Cider Vinegar (ACV) liquid on postprandial glucose (PPG) excursion compared ...

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC8243436/

The effect of apple cider vinegar on lipid profiles and ... ACV consumption significantly decreased serum total cholesterol, fasting plasma glucose, and HbA1C, showing a favorable effect on blood lipid ...

4. heart.org heart.org/en/news/2024/09/11/what-can-apple-cider-vinegar-really-do-for-your-health

What can apple cider vinegar really do for your health? Several studies have found that consuming apple cider vinegar daily could slightly reduce fasting blood glucose and A1C – a test that measures ...

5. mdpi.com mdpi.com/2072-6643/17/18/3000

Effect of Apple Cider Vinegar Intake on Body Composition ... In particular, ACV has shown promising effects in improving glycemic control and insulin sensitivity [28,29,30], lipid profiles [28,29,30], and reducing ...

6. uchicagomedicine.org uchicagomedicine.org/forefront/health-and-wellness-articles/2018/august/debunking-the-health-benefits-of-apple-cider-vinegar

Debunking the health benefits of apple cider vinegar Bottom line: ACV won't cure diabetes, but it may moderately lower blood glucose levels. It won't take the place of any medications for diabetes, ...

7. webmd.com webmd.com/diet/apple-cider-vinegar-and-your-health

Apple Cider Vinegar: Benefits, Risks, and Uses Keep in mind that vinegar can't replace diabetes medications and a healthy lifestyle, but it should be safe to add to your treatment plan.