Transcendental Meditation vs Present Centered Therapy for PTSD
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you must stop taking your current medications, but it does mention that you should not change the dosage of or start new psychotropic medications during the study. If you have recently changed your medication dosage or started a new one within the last three months, you may not be eligible to participate.
What data supports the effectiveness of the treatment Transcendental Meditation (TM) for PTSD?
Research shows that Transcendental Meditation (TM) can help reduce PTSD symptoms. In one study, veterans practicing TM had significant improvements in PTSD symptoms, with 50% no longer meeting PTSD criteria, compared to 10% in the control group. Another study found that TM reduced the need for medications in military members with PTSD.12345
Is Transcendental Meditation safe for humans?
How does the treatment of Transcendental Meditation differ from other treatments for PTSD?
Transcendental Meditation (TM) is unique because it involves using a mantra to facilitate meditation, which is a non-drug approach to managing PTSD symptoms. Unlike traditional therapies that focus on discussing trauma, TM offers a mental technique that can be practiced independently, potentially reducing stress and improving mental well-being.14578
What is the purpose of this trial?
This trial tests two treatments, Transcendental Meditation (TM) and Present Centered Therapy (PCT), for veterans and first responders with PTSD. TM uses meditation to calm the nervous system, while PCT focuses on current issues and coping strategies. Early research shows that Transcendental Meditation (TM) can help with PTSD. The goal is to find helpful treatments for PTSD in this group.
Research Team
Yuval Neria, PhD
Principal Investigator
NYSPI and Columbia University
Eligibility Criteria
This trial is for right-handed veterans and first responders aged 18-80 with PTSD, who can consent and are English literate. They must have a CAPS-5 score ≥ 25 and symptoms for at least 3 months. Exclusions include severe substance use disorders (except nicotine), unstable medical conditions, certain metal implants, claustrophobia in MRI scanners, recent psychiatric hospitalization or medication changes, pregnancy/breastfeeding women, current psychotherapy or meditation therapy users.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either Transcendental Meditation (TM) or Present Centered Therapy (PCT) for PTSD
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Present Centered Therapy (PCT)
- Transcendental Meditation (TM)
Find a Clinic Near You
Who Is Running the Clinical Trial?
Research Foundation for Mental Hygiene, Inc.
Lead Sponsor
Mount Sinai Hospital, New York
Collaborator
David Lynch Foundation
Collaborator
Stanford University
Collaborator
University of Southern California
Collaborator
Brown University
Collaborator
Icahn School of Medicine at Mount Sinai
Collaborator
New York State Psychiatric Institute
Collaborator
Northwell Health
Collaborator
University of California, San Diego
Collaborator