Your session is about to expire
← Back to Search
Transcendental Meditation vs Present Centered Therapy for PTSD
N/A
Recruiting
Led By Yuval Neria, PhD
Research Sponsored by Research Foundation for Mental Hygiene, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline, at 6 weeks, post-treatment: approximately 3 months and 6 months from intake
Awards & highlights
Study Summary
This trial is researching two treatments for PTSD in veterans and first responders: Transcendental Meditation and Present Centered Therapy. It will last 3 years and include assessments & MRI scans.
Who is the study for?
This trial is for right-handed veterans and first responders aged 18-80 with PTSD, who can consent and are English literate. They must have a CAPS-5 score ≥ 25 and symptoms for at least 3 months. Exclusions include severe substance use disorders (except nicotine), unstable medical conditions, certain metal implants, claustrophobia in MRI scanners, recent psychiatric hospitalization or medication changes, pregnancy/breastfeeding women, current psychotherapy or meditation therapy users.Check my eligibility
What is being tested?
The study compares Transcendental Meditation (TM) with Present Centered Therapy (PCT) in treating PTSD. Participants will be randomly assigned to one of the treatments and assessed five times over six months via videoconferencing. The New York State Psychiatric Institute/Columbia protocol includes pre-and post-treatment MRIs to study brain changes.See study design
What are the potential side effects?
While not explicitly stated for this trial, common side effects from meditation practices like TM may include discomfort during practice or increased awareness of negative feelings. PCT generally has minimal side effects but could potentially cause distress when discussing traumatic events.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline, at 6 weeks, post-treatment: approximately 3 months and 6 months from intake
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline, at 6 weeks, post-treatment: approximately 3 months and 6 months from intake
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in PTSD symptoms over time
Secondary outcome measures
Change in depressive symptoms over time
Trial Design
2Treatment groups
Active Control
Group I: Present Centered Therapy (PCT):Active Control1 Intervention
PCT is a focused time-limited treatment for PTSD that focuses on increasing adaptive responses to current life stressors and difficulties that are directly or indirectly related to trauma or PTSD symptoms. PCT was originally designed as a treatment comparator in trials evaluating the effectiveness of trauma-focused cognitive-behavioral therapies such as PE and CPT. Several clinical trials have indicated that PCT may be an effective treatment option for PTSD and that patients may drop out of PCT at lower rates relative to trauma focused forms of CBT.
Group II: Transcendental Meditation (TM):Active Control1 Intervention
TM treatment for PTSD is designed to reduce stress, facilitate deep rest, and increase well-being. It was originally conceptualized as an effortless technique to enable physical relaxation. The treatment will be delivered by experienced, certified TM instructors receiving weekly supervision.
Find a Location
Who is running the clinical trial?
Mount Sinai Hospital, New YorkOTHER
34 Previous Clinical Trials
891,238 Total Patients Enrolled
David Lynch FoundationOTHER
3 Previous Clinical Trials
580 Total Patients Enrolled
Stanford UniversityOTHER
2,395 Previous Clinical Trials
17,340,990 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I haven't changed or started any mental health medications in the last 3 months.I have never been diagnosed with a psychotic disorder or schizophrenia.I plan to change or start new mental health medication during the study.I have been diagnosed with PTSD and have had symptoms for at least 3 months.I have a serious illness that is not under control.I do not have any illnesses like severe brain issues or uncontrolled thyroid disease that could affect my diagnosis.I am not pregnant, breastfeeding, nor planning to become pregnant during the study.I am between 18 and 80 years old.I have previously or am currently practicing Transcendental Meditation, Present Centered Therapy, or another form of psychotherapy.I have been diagnosed with bipolar disorder.I plan to start or change my psychotherapy or meditation therapy during the study.
Research Study Groups:
This trial has the following groups:- Group 1: Present Centered Therapy (PCT):
- Group 2: Transcendental Meditation (TM):
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is the research project seeking participants of a certain age or above?
"The minimum requirement for potential participants of this medical trial is 18 years old, while the maximum age limit stands at 80."
Answered by AI
What population qualifies to participate in this clinical investigation?
"Candidates with PTSD aged between 18 and 80 can apply to be enrolled in this trial. The total number of patients that will be accepted is approximately 360."
Answered by AI
Is enrollment still open for this research endeavor?
"As relayed on clinicaltrials.gov, this medical experiment has commenced its recruitment process as of December 12th 2022 and the details have been revised on December 28th 2022."
Answered by AI
What is the upper-bound of participants in this experiment?
"Affirmative. Clinicaltrials.gov data confirms that this clinical study is presently seeking participants, which was originally posted on December 12th 2022 and recently updated on the 28th of December. As part of their recruitment efforts, they are in search of 360 patients from a single medical facility."
Answered by AI
Who else is applying?
What site did they apply to?
New York State Psychiatric Institute
What portion of applicants met pre-screening criteria?
Did not meet criteria
How many prior treatments have patients received?
3+
Why did patients apply to this trial?
I’m tired of suffering with my PTSD. I just want some relief from it. Even if it’s only a short time.
PatientReceived 2+ prior treatments
Recent research and studies
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger