DNA Study for Vasculitis
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to uncover genetic factors that might increase the risk of developing vasculitis, a serious condition where blood vessels become inflamed. By studying DNA, researchers hope to gain insights that could lead to better diagnostic tests and treatments for vasculitis and similar diseases. Individuals with specific types of vasculitis, such as Giant Cell Arteritis or Takayasu's Arteritis, who have experienced symptoms like severe headaches or reduced artery pulse, might be suitable for this study. Participants will provide a one-time DNA sample for analysis in this One-Time DNA Study. As an unphased study, this trial offers participants the chance to contribute to groundbreaking research that could improve future diagnostic and treatment options for vasculitis.
Do I have to stop taking my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Why are researchers excited about this trial?
Researchers are excited about the One-Time DNA Study for vasculitis because it offers a groundbreaking approach to understanding and potentially treating the condition. Unlike conventional treatments that often involve long-term use of immunosuppressive drugs to manage symptoms, this study aims to uncover genetic insights that could lead to more personalized and effective treatments. By focusing on the genetic underpinnings of vasculitis, this approach has the potential to identify new therapeutic targets and tailor treatments to individual patients, enhancing both effectiveness and safety.
Who Is on the Research Team?
Peter Merkel, MD, MPH
Principal Investigator
University of Pennsylvania
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Data Collection
One-time collection of clinical data and DNA from participants
Follow-up
Participants are monitored for safety and effectiveness after data collection
What Are the Treatments Tested in This Trial?
Interventions
- One-Time DNA Study
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Pennsylvania
Lead Sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborator
Office of Rare Diseases (ORD)
Collaborator
Rare Diseases Clinical Research Network
Collaborator