Facial Creams for Photoaging
Trial Summary
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but if you are taking a medication that could affect the study results, you may not be eligible to participate.
What data supports the effectiveness of the drug Facial Cream A or Facial Cream B for photoaging?
Research shows that topical retinoids, like isotretinoin, improve the appearance of photodamaged skin by reducing wrinkles and improving skin texture. Additionally, a combination of retinol, lactose, and glycolic acid has been shown to significantly improve photodamaged skin, suggesting that similar ingredients in facial creams could be effective.12345
Is there any safety data available for facial creams used in clinical trials?
How does Facial Cream A and Facial Cream B differ from other treatments for photoaging?
Facial Cream A and Facial Cream B may offer a unique approach to treating photoaging by potentially incorporating ingredients like isotretinoin, which is known for its anti-acne properties but also has anti-aging potential, although it can be irritating to the skin. This differs from other treatments like tazarotene and tretinoin creams, which are retinoids specifically studied for their effectiveness in reducing signs of photoaging.1112131415
What is the purpose of this trial?
The objective of this study is to evaluate the efficacy of a retinol alternative-containing facial cream in improving skin texture, radiance/brightness, and the appearance of fine lines, wrinkles, uneven skin tone, and dark spots, with a positive control of a retinol-containing cream.
Eligibility Criteria
This trial is for individuals with moderate to severe photodamaged skin, who are generally healthy and have Fitzpatrick Skin Type I-IV. Participants must understand English, agree to photo consent, and follow study instructions. Excluded are those with allergies to skincare ingredients, very sensitive skin, diabetes, certain health risks or conditions that could affect results, pregnant or lactating women, and anyone in another study within the last 30 days.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants use either Facial Cream A or Facial Cream B for 12 weeks to evaluate efficacy on photodamaged skin
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Facial Cream A
- Facial Cream B
Find a Clinic Near You
Who Is Running the Clinical Trial?
Johnson & Johnson Consumer Inc. (J&JCI)
Lead Sponsor