33 Participants Needed

Atomic App for Pediatric Cancer Survivors

OH
TL
Overseen ByTiffany L Ruiz, BSN
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: Connecticut Children's Medical Center
Must be taking: Anthracycline therapy
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the ATOMIC Mobile App treatment for pediatric cancer survivors?

Research shows that digital health interventions, like mobile apps, are feasible and acceptable for childhood cancer survivors, helping them manage their health after treatment. While specific data on the ATOMIC Mobile App is not available, similar apps have been used to support medication adherence and symptom management in oncology patients.12345

Is the Atomic App for Pediatric Cancer Survivors safe for use?

There is no specific safety data available for the Atomic App or its other names like ATOMIC or ATOMIC Mobile App. However, digital health interventions in general have been found to be feasible and acceptable for pediatric cancer survivors.36789

How is the ATOMIC Mobile App treatment different from other treatments for pediatric cancer survivors?

The ATOMIC Mobile App is unique because it focuses on providing support and resources through a digital platform specifically designed for pediatric cancer survivors, which is different from traditional treatments like radiotherapy or chemotherapy that directly target cancer cells. This app may offer tools for managing long-term health and quality of life, which are not typically addressed by standard cancer treatments.1011121314

What is the purpose of this trial?

Development and Usability Testing of the ATOMIC Mobile App to Increase Physical Activity (PA) Levels in Children, Adolescent and Young Adults (AYA) survivors of childhood cancer

Research Team

OH

Olga H Toro-Salazar, MD

Principal Investigator

CT Children's Medical Center

Eligibility Criteria

This trial is for childhood cancer survivors aged 10 to 30 who can speak English fluently. They must have been treated with anthracycline therapy. It's not suitable for those unable to cooperate in interviews, non-English speakers, or anyone unable to understand interview content.

Inclusion Criteria

I am between 10 and 30 years old.
My child's cancer treatment includes anthracycline therapy.

Exclusion Criteria

Unable to understand the content of interviews
I am a child cancer survivor not scheduled for anthracycline therapy.
I am unable to participate in interviews.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Usability Testing

Participants engage in 'real life' usability testing of the ATOMIC mobile app, performing individualized aerobic and resistance exercise interventions

4 weeks
4-5 sessions per week

Follow-up

Participants are monitored for ease of use and user errors during usability testing, and acceptability is assessed using the Acceptability E-Scale

1 year

Treatment Details

Interventions

  • ATOMIC
Trial Overview The ATOMIC mobile app is being tested for its ability to increase physical activity levels among children and young adults who survived pediatric cancer. The study involves development and usability testing of the app specifically designed for this group.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: Real life usability testingExperimental Treatment1 Intervention
B) "Real Life" Usability Testing. We will conduct a "real life" usability test in a sample of 6 pediatric cancer survivors. EX@HOME: Patients will perform an individualized aerobic and resistance exercise intervention, choosing from a list of PA, progressing from light to moderate-to-vigorous intensity totaling 30-45 min/d, 4-5 weekly/wk. for 4 weeks. The social-cognitive-theory-based mobile app will support the exercise intervention. One-on-one messaging chats with a PA coach through the mobile app will facilitate exercise goal establishment and attainment.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Connecticut Children's Medical Center

Lead Sponsor

Trials
76
Recruited
30,000+

The Hospital for Sick Children

Collaborator

Trials
724
Recruited
6,969,000+

Findings from Research

The study demonstrated that collecting weekly electronic patient-reported outcome measures (ePROMs) from 70 pediatric cancer patients and their caregivers is feasible, with 69% completing the assessments over 8 weeks.
While distress and cancer-related quality of life improved over time, nearly half of the participants still reported high distress levels by the end of the study, indicating a need for ongoing assessment and timely interventions to address persistent symptoms and improve overall patient care.
Feasibility of Weekly Electronic Patient- and Proxy-Reported Outcome Measures in Pediatric Oncology.Skrabal Ross, X., Condon, P., Yates, P., et al.[2023]
A systematic review of eight studies on digital self-management interventions for childhood cancer survivors found that these interventions did not significantly improve health-related quality of life or moderate-to-vigorous physical activity, indicating limited effectiveness.
While the interventions showed a trend towards increasing physical activity over time, the results were not statistically significant, highlighting the need for better-designed studies to assess their true impact on health outcomes.
The effectiveness of digital self-management interventions on health outcomes among childhood cancer survivors: A systematic review and meta-analysis.Hong, HC., Min, A., Kim, YM.[2021]
Digital health interventions are generally well-received by pediatric cancer survivors, providing benefits such as self-awareness, social connection, and empowerment, based on a systematic review of 16 qualitative studies.
However, users also face challenges related to program content, technology, and personal usage, highlighting the need for tailored interventions to enhance their effectiveness and user satisfaction.
The Pediatric Cancer Survivors' User Experiences With Digital Health Interventions: A Systematic Review of Qualitative Data.Cheng, L., Liu, F., Mao, X., et al.[2022]

References

Feasibility of Weekly Electronic Patient- and Proxy-Reported Outcome Measures in Pediatric Oncology. [2023]
The effectiveness of digital self-management interventions on health outcomes among childhood cancer survivors: A systematic review and meta-analysis. [2021]
The Pediatric Cancer Survivors' User Experiences With Digital Health Interventions: A Systematic Review of Qualitative Data. [2022]
The Use and Effect of the Health Storylines mHealth App on Female Childhood Cancer Survivors' Self-efficacy, Health-Related Quality of Life and Perceived Illness. [2022]
Evaluation of mobile phone applications to support medication adherence and symptom management in oncology patients. [2019]
A global approach to long-term follow-up of targeted and immune-based therapy in childhood and adolescence. [2022]
The first step to integrating the child's voice in adverse event reporting in oncology trials: a content validation study among pediatric oncology clinicians. [2021]
Development of a Pediatric Adverse Events Terminology. [2019]
Adolescents' understanding of chemotherapy-related adverse events: a concept elicitation study. [2022]
QUARTET: A SIOP Europe project for quality and excellence in radiotherapy and imaging for children and adolescents with cancer. [2022]
11.United Statespubmed.ncbi.nlm.nih.gov
The role of proton therapy in pediatric malignancies: Recent advances and future directions. [2020]
A dedicated cloud system for real-time upfront quality assurance in pediatric radiation therapy. [2020]
The European Society of Paediatric Oncology Ependymoma-II program Core-Plus model: Development and initial implementation of a cognitive test protocol for an international brain tumour trial. [2019]
Clinical research tools in pediatric oncology: challenges and opportunities. [2020]
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