Low GI Diet for Leukemia
Trial Summary
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the Low Glycemic Index Diet treatment for leukemia?
Research suggests that dietary interventions, like fasting or caloric restriction, can help in treating leukemia by affecting certain biological pathways. For example, fasting has been shown to inhibit leukemia progression in mice by upregulating leptin-receptor signaling, and caloric restriction has been associated with improved chemotherapy outcomes in leukemia patients.12345
Is the Low GI Diet safe for humans?
How does the Low GI Diet treatment for leukemia differ from other treatments?
The Low GI Diet treatment is unique because it focuses on dietary changes by limiting foods with a high glycemic index (which measure how quickly foods raise blood sugar levels), rather than using medications. This approach is novel for leukemia as it is typically used for managing conditions like epilepsy and diabetes, where controlling blood sugar levels is crucial.89101112
What is the purpose of this trial?
The study aims to determine the feasibility of a 6-month low glycemic dietary intervention in children and adolescents undergoing treatment for acute lymphoblastic leukemia.
Research Team
Elena Ladas, PhD
Principal Investigator
Columbia University
Eligibility Criteria
This trial is for children and adolescents who have been diagnosed with Acute Lymphoblastic Leukemia (ALL), including B-Cell, T-Cell, or Mixed Phenotype. They must be within 3 days of starting the induction phase of their treatment and able to understand English or Spanish.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants follow a low glycemic index diet for 6 months while undergoing treatment for ALL
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Low Glycemic Index Diet
Find a Clinic Near You
Who Is Running the Clinical Trial?
Columbia University
Lead Sponsor
American Cancer Society, Inc.
Collaborator
Gabrielle's Angel Foundation
Collaborator